[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

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Ingredients
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Other Ingredients
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(Sendt lørdag d. 1. februar 2014 på DR1)

Et stigende salg af naturmedicin som perikon er rigtigt positiv udvikling og viser sandsynligvis tendenser, så som at folk:
• er blevet mere ansvarlige for deres eget helbred
• er mere bevidste om hvad de putter i munden
• er mere påpasselige over for læger og medicinalbranchen
• vælger så naturlige og ufoarbejdede varer som muligt
• vælger præparater med så få bivirkninger som muligt

Depressionsforsker Poul Videbech (0:43): “Hvis man har let depression skal man slet ikke have medicin, og det er jo medicin det vi snakker om.”
Modsvar:
• “Considering the favourable safety profile of all extracts studied … which also correlated with a lower frequency of dropouts in clinical studies than seen with standard antidepressants, Hypericum extract is a valid therapeutic approach in patients with mild to moderate depression.” https://livar.net/UploadedFiles/Article/EfficacyandolerabilityofHypericumExtractfortheTreatment.pdf
• “Primary care physicians in [German-speaking] countries use Hypericum extracts mainly in patients with mild to moderate depressive complaints…” https://dcscience.net/st-johns-wort-linde.pdf

Poul Videbech (0:48): “…og har man en moderat til en svær depression, så har man altså brug for støtte fra en udenforstående person, altså ens praktiserende læge.”
Modsvar:
• Læger mangler tid til svage patienter https://forsiden.3f.dk/article/20110329/NYHEDER/110319932/2086
• “Brugen af psykofarmaka kunne mindskes, hvis praktiserende læger fik bedre tid til patienter med psykiske problemer, mener formanden for landets psykiatere.” https://information.dk/484953
• Travlhed: Jørgen har over 5.000 patienter “Når Jørgen Saaby stopper, vil det kræve 3-4 læger at erstatte ham.” https://pol.dk/ECE1844819
• Nyuddannede læger: Vi har for travlt https://jv.dk/artikel/1582558
• “Kun en fjerdedel af arbejdstiden for hospitalslæger bliver brugt med patienterne.” https://dr.dk/Nyheder/Indland/2012/03/20/180658.htm
• “…Danilo Terrida. Han følte sig deprimeret og fik udskrevet lykkepiller af mærket Sertralin af sin egen læge. Det skete via telefonen og tog 8 minutter.” https://dr.dk/arkivP1/P1Dokumentar/Udsendelser/Andet/20120412175458.htm

Poul Videbech om hvis man begynder at behandle sig selv mod svær depression (1:05): “… så kan man jo se det, at der lige pludselig dukker selvmordstanker op, ikke også. Måske selvmordsforsøg.”
Modsvar:
• “When adult antidepressant trials were re-analyzed to compensate for erroneous methodologies, SSRIs have consistently revealed a risk of suicide (completed or attempted) that is two to four times higher than placebo.” https://chriskresser.com/the-dark-side-of-antidepressants
• “Unlike some of the responses to a previous meta-analysis of antidepressant drug effects (I. Kirsch and G. Sapirstein, 1998), there is now unanimous agreement among commentators that the mean difference between response to antidepressant drugs and response to inert placebo is very small. It is so small that, despite sample sizes involving hundreds of participants, 57% of the trials funded by the pharmaceutical industry failed to show a significant difference between drug and placebo.”

https://psycnet.apa.org/journals/pre/5/1/33r.html‎

• Antidepressants No Better Than Placebo: JAMA Study https://greenmedinfo.com/blog/antidepressants-no-better-placebo-jama-study
• Peter C. Gøtzsche – https://youtube.com/watch?v=i1LQiow_ZIQ

I indslaget siger Jonna Andersen – salgsassistent fra Ren Kost og Krop – bl.a.: (0:33) “Vi har klart oplevet en stigning. Specielt fra omkring juletid.” Dette er positivt, både fordi folk er opmærksomme på at de måske kan være på vej til at få vinterdepression men også fordi perikon netop gør en mere lysføslom. Dette egenskab gør perikon oplagt at tage netop om vinteren, fordi den øger hudens modtagelse af sollys, netop i en tid hvor vi har mindst sollys. Dermed kan kroppen sandsynligvis også danne mere D-vitamin, samt at mere opfattet lys – pga. overfølsomheden – i sig selv også har en positiv indvirkning på humøret.
• “Øget lysfølsomhed bliver ofte nævnt i sammenhæng med Perikum. Faktisk reagerer huden stærkere på sollys efter indtagelse af urten.” https://drhauschka-med.dk/kvalitet/plantelex/perikum
• One Hour of Light Therapy Reduces Depression https://greenmedinfo.com/blog/one-hour-light-therapy-reduces-depression

_ Om hvorfor læger misinformerer eller selv er misinformerede_
• (2011) Medicinalindustrien ejer medicin.dk, hvor de praktiserende læger søger information om bivirkninger. https://information.dk/269628
• (2011) Medicinalindustriens forskningsfusk og de købte læger

https://videnskab.dk/medicinalindustriens-forskningsfusk-og-de-kobte-laeger

• (2013) Praktiserende læger: Stærke kræfter vil udvide medicinforbrug https://dr.dk/Nyheder/Indland/2013/04/15/124406.htm