[Latin Name] Vitis vinifera Linn

[Plant Source] Grape seed from Europe

[Specifications] 95%OPCs；45-90% polyphenols

[Appearance] Red brown powder

[Plant Part Used]: seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Gerneral feature]

1. Our product has passed the ID test by ChromaDex, Alkemist Lab. and other

third-party authoritative testing institutions, such as detection;

2. The pesticide residues match (EC) No 396/2005 USP34, EP8.0, FDA and other foreign pharmacopoeia standards and regulations;

3. The heavy metals in strict accordance with the foreign pharmacopoeia standard controls, such as USP34, EP8.0, FDA, etc.;

4. Our company set up a branch and import raw materials directly from Europe with strict control of heavy metal and pesticide residue. Aslo ensure the procyanidins content in grape seed is more than 8.0%.

5. OPCs over 95%, polyphenol over 70%, high activity, the oxidation resistance is strong, the ORAC more than 11000.

[Function]

Grapes (Vitis vinifera) have been heralded for their medicinal and nutritional value for thousands of years. Egyptians ate grapes a very long time back, and several ancient Greek philosophers spoke about the healing power of grapes — usually in the form of wine. European folk healers made an ointment from the sap of grapevines to treat skin and eye diseases. Grape leaves were used to stop bleeding, inflammation, and pain, such as the kind brought on by hemorrhoids. Unripe grapes were used to treat sore throats, and dried grapes (raisins) were used for constipation and thirst. Round, ripe, sweet grapes were used to treat a range of health problems including cancer, cholera, smallpox, nausea, eye infections, and skin, kidney, and liver diseases.

Grape seed extracts are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid and phenolic OPCs. The typical commercial opportunity of extracting grape seed constituents has been for chemicals known as polyphenols having antioxidant activity in vitro.

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Belgian biochemist Christian de Duve (1917-2013) was best known for his work on understanding and categorising subcellular organelles. He won the Nobel Prize in Physiology or Medicine in 1974 for his joint discovery of lysosomes, the subcellular organelles that digest macromolecules and deal with ingested bacteria. [Listener: Peter Newmark]

TRANSCRIPT: And so, a year later, another patient with the disease was detected at the University of Brussels and Pierre Baudhuin in our laboratory did a microscopic… electron microscopic examination on the biopsy fragment of the liver of that child because, by that time, we had acquired an electron microscope and Baudhuin and Beaufay were the main experts and so they found that, indeed, the glycogen, or much of the glycogen in this pathological sample, was surrounded by a membrane, was confined within a sac-like particle which, presumably, was a lysosome, and this indeed turned out to be the case. And so, in this way, he discovered the first lysosomal storage disease which he then went on to generalise into a major concept, the concept of an inborn lysosomal disease being that in the cells all kinds of materials – lipids, polysaccharides, you name it, they are there – get into lysosomes, sometimes by endocytosis but most of the time by autophagy. Those materials are then digested in the lysosomes by… 50 or more enzymes are now known… broken down… the products of the breakdown… the breakdown products go through the membrane, are utilised by the cell, and this goes on and on and on. But if one of those enzymes happens to be missing or deficient then among all this material, those molecules that require the missing enzyme to be broken down, would accumulate. And so, depending on the nature of the missing enzyme, you would have a different kind of chemical material accumulating, always in the lysosomes. Now, that was a tremendously fruitful concept – it was a paper published in Gastroenterology in 1965 –and it has a major impact on the whole field because, for a number of… many years the whole category of diseases was known; they were called storage diseases, they were genetic diseases – in French they were called thesaurismoses… thesaurismosis, essentially due to their abnormal storage of materials within cells, and those could be mucopolysaccharides of one form or another… in Hurler or Hunter Disease, could be lipids of one form or another; or another, glucocerebrosides, glycolipids, in Gaucher’s Disease, in Fabry’s Disease; sphingomyelin in Niemann-Pick Disease. I mean, these diseases all have the names of the physicians who described them but there was a whole mysterious chapter of pathology and literally, from one day to the other, the whole thing was clarified. Of course it needed many investigations by a number of really very good biochemists, mostly in the United States, to actually identify the missing enzyme and… clarifying the whole field. So that was a major… a major contribution which interestingly was made through the lysosome field by the only one in my group who had actually decided he didn’t want to have anything to do with them, but that’s life.