[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

Ever tried pumpkin spiced pickled pigs feet? GMM #555!
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“In Search of the (Membrane) Holy Grail: A 20-Year Journey”

Mark Benjamin
Civil and Environmental Engineering, University of Washington

ABSTRACT: Natural organic matter (NOM) is universally recognized as a major foulant of membranes used for drinking water treatment. The fouling has been attributed to adsorption of NOM in membrane pores and/or to formation of a gel layer that covers the membrane surface. Colloids, humics, and polysaccharides have each been implicated as major contributors to this fouling material. Most efforts to reduce the impact of this fouling have focused on pretreatment with conventional coagulants or powdered activated carbon.
We have developed a new micron-sized, granular adsorbent by mild heating of aluminum hydroxide and demonstrated that it can adsorb NOM rapidly and more efficiently than conventional additives. In addition, a cake layer of the new adsorbent imposes very little hydraulic resistance. As a result, when these adsorbents are used as the media for precoat filtration, a substantial portion of the NOM can be removed from the feed with only a few seconds of contact time, thereby reducing DBP formation potential and also dramatically reducing the fouling of downstream membranes. Our recent research has focused identifying the chemical characteristics of the fouling fraction of the NOM, on ways to efficiently backwash the adsorbents off of the support material after their capacity to collect the contaminants has been exhausted, and on regeneration of adsorbent.
At virtually every step in the research, we have encountered unexpected and challenging issues, many of which we have overcome, but others of which we continue to struggle with. The presentation will provide an overview of the successes, the frustrations, and the excitement we still feel about the potential of this new process.