[Latin Name] Andrographis paniculata(Burm.f.)Nees

[Plant Source] Whole herb

[Specification] Andrographolides 10%-98% HPLC

[Appearance] White powder

Plant Part Used: Herb

[Particle size] 80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is Andrographis?]

Andrographis paniculata is a bitter tasting annual plant, referred to as the “King of Bitters.” It has white-purple flowers and it is native to Asia and India where it has been valued for centuries for its numerous medicinal benefits. Over the past decade, andrographis has become popular in America where it is often used alone and in combination with other herbs for a variety of health purposes.

[How does it work?]

According to Memorial Sloan-Kettering Cancer Center, the active ingredient in andrographis is andrographolides. Due to the andrographolides, andrographis has potent anti-inflammatory and antimalarial properties. It also has antimicrobial properties, meaning it can help to fight off and prevent infections from harmful microorganisms such as viruses, bacteria and fungi. In addition, andrographis is a powerful antioxidant and it can help to prevent free radical induced damage to your cells and DNA

[Function]

Cold and Flu

Scientists have discovered that andrographis helps to boost the immune system by stimulating the body’s production of antibodies and macrophages, which are large white blood cells that scavenge harmful microorganisms. It is taken for both the prevention and treatment of the common cold, and it is often referred to as Indian echinacea. It might help lessen the severity of cold symptoms such as sleeplessness, fever, nasal drainage and sore throat.

Cancer, Viral Infections and Heart Health

Andrographis may also help to prevent and treat cancer, and preliminary studies done in test tubes found that extracts of andrographis help to treat stomach, skin, prostate and breast cancer. Due to the herb’s antiviral properties, andrographis is used to treat herpes and it is also currently being studied as a treatment for Aids and HIV as well. Andrographis also promotes heart health and can help to prevent the formation of blood clots as well as to dissolve already formed blood clots. In addition, the herb relaxes smooth muscles in the walls of blood vessels and thereby helps to reduce high blood pressure.

Additional Benefits

Andrographis is used to promote gallbladder and digestive health. It also helps to support and strengthen the liver and it is used in combination with other herbs in several Ayurvedic formulations to treat liver disorders. Finally, andrographis extracts taken orally have been found to help neutralize the poisonous effects of snake venom.

Dosage and Precautions

The therapeutic dose of andrographis is 400 mg, twice daily, for up to 10 days. Although andrographis is considered safe in humans, the NYU Langone Medical Center warns that animal studies suggest that it may impair fertility. Andrographis may cause unwanted side effects such as headaches, fatigue, allergic reactions, nausea, diarrhea, altered taste and pain in the lymph nodes. It may also interact with certain medications and as with any supplement you should consult your health care practitioner before taking the herb.

Professor Maureen McCann, Director of the Energy Center at Purdue University, addresses “A Roadmap for Selective Deconstruction of Lignocellulosic Biomass to Advanced Biofuels and Useful Co-Products” on February 11, 2013 as part of the Andlinger Center’s 2012-2013 Highlight Seminar Series.

ABSTRACT
Second-generation biofuels will be derived from lignocellulosic biomass using biological catalysis to use the carbon in plant cell wall polysaccharides for ethanol or other biofuels. However, this scenario is both carbon- and energy-inefficient. The major components of biomass are cellulose, hemicellulose and lignin. Biological conversion routes utilize only the polysaccharide moiety of the wall, and the presence of lignin interferes with the access of hydrolytic enzymes to the polysaccharides. Living micro-organisms, required to ferment released sugars to biofuels, utilize some sugars in their own growth and co-produce carbon dioxide. In contrast, chemical catalysis has the potential to transform biomass components directly to alkanes, aromatics, and other useful molecules with improved efficiencies. The Center for Direct Catalytic Conversion of Biomass to Biofuels (C3Bio) is a DOE-funded Energy Frontier Research Center, comprising an interdisciplinary team of plant biologists, chemists and chemical engineers. We are developing catalytic processes to enable the extraction, fractionation, and depolymerization of cellulose and hemicellulose coupled to catalytic transformation of hexoses and pentoses into hydrocarbons. Additional catalysts may cleave the ether bonds of lignin to release useful aromatic co-products or that may oxidize lignols to quinones. In a parallel approach, fast-hydropyrolysis is a relatively simple and scalable thermal conversion process. Our understanding of biomass-catalyst interactions require novel imaging and analysis platforms, such as mass spectrometry to analyze potentially complex mixtures of reaction products and transmission electron tomography to image the effects of applying catalysts to biomass and to provide data for computational modeling. By integrating biology, chemistry and chemical engineering, our data indicate how we might modify cell wall composition, or incorporate Trojan horse catalysts, to tailor biomass for physical and chemical conversion processes. We envision a road forward for directed construction and selective deconstruction of plant biomass feedstock.

BIOGRAPHY
Maureen McCann is the Director of Purdue’s Energy Center, part of the Global Sustainability Initiative in Discovery Park. She obtained her undergraduate degree in Natural Sciences from the University of Cambridge, UK, in 1987, and then a PhD in Botany at the John Innes Centre, Norwich UK, a government-funded research institute for plant and microbial sciences. She stayed at the John Innes Centre for a post-doctoral, partly funded by Unilever, and then as a project leader with her own group from 1995, funded by The Royal Society. In January 2003, she moved to Purdue University as an Associate Professor, and she is currently a Professor in the Department of Biological Sciences.

The goal of her research is to understand how the molecular machinery of the plant cell wall contributes to cell growth and specialization, and thus to the final stature and form of plants. Plant cell walls are the source of lignocellulosic biomass, an untapped and sustainable resource for biofuels production with the potential to reduce oil dependence, improve national security, and boost rural economies. She is also the Director of the Center for Direct Catalytic Conversion of Biomass to Biofuels (C3Bio), an interdisciplinary team of biologists, chemists and chemical engineers in an Energy Frontier Research Center funded by the US Department of Energy’s Office of Science.

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