[Latin Name]  Piper methyicium L.

[Specification] Kavalactones ≥30.0%

[Appearance] Yellow powder

Plant Part Used: Root

[Particle size] 80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is Kava?]

Kava, also known as piper methysticum, kava kava, and ‘awa, is a small shrub native to the islands in the South Pacific. The root and stems are made into a non-alcoholic, psychoactive beverage that has been used socially and ceremonially for hundreds of years in Hawaii, Fiji, and Tonga.

Kava is traditionally prepared by placing ground root and stem into a porous sack, submerging in water, and squeezing the juice into a large, carved, wooden bowl. Coconut half-shell cups are dipped and filled — punch bowl style. After drinking a cup or two a feeling of heightened attention combined with relaxation begins to come on. Although it is soothing, it is unlike alcohol in that thoughts remain clear. The flavor is largely inoffensive, but some find that it takes getting used to; it really depends on your preference for earthy flavors.

[Kava is Safe to Use]

The safe and effective benefits of kava to relieve symptoms of anxiety were also supported in a meta-analysis, a systematic statistical review of seven human clinical trials published in 2000 in the Journal of Clinical Psychopharmacology, and again in a similar critical review in 2001. The reviews did not find significant adverse effects related to liver toxicity.

In conclusion, the liver is affected by many substances, including prescription and non- prescription drugs, as well as alcohol, which is a major cause of liver damage. We must be aware that herbs are potent medicines, to be treated with the appropriate respect regarding potential interactions and toxicity, including to the liver. On the other hand, Kava kava’s margin of safety far surpasses that of it’s pharmaceutical equivalent.

[Function]

Kava’s can help offset a number of problems, most notably stress, anxiety, and disrupted sleep patterns. However, kava’s anxiolytic (anti-panic or anti-anxiety agent) and calming properties can offset many other stress and anxiety related ailments.

1. Kava as a Therapy for Anxiety
2. Kava May Remedy Menopausal Mood Swings

3. Weight Loss

4. Combat Premature Aging

5. Quit Smoking Aid

6. Combat pain as an analgesic

7. Insomnia

8. Depression

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Moof’s Medical Biochemistry Video Course: https://moof-university.thinkific.com/courses/medical-biochemistry-for-usmle-step-1-exam

For Related Practice Problems with Worked Video Solutions on Carbohydrates, visit courses.moofuniversity.com.

In this video, I introduce the topic of carbohydrates / sugars.

(CH2O)n is the general formula for a monosaccharide or simple sugar. Glucose (C6H12O6) is a very common and very important example.

Carbohydrate names end in “-ose”
Aldoses have aldehydes in their straight-chain forms (depicted as Fischer projections)
Ketones have ketones in their straight-chain forms (depicted as Fischer projections)

There are D sugars and L sugars, and the convention is based on the Fischer projections of D-glyceraldehyde and L-glyceraldehyde. The two are enantiomers because they are opposite in absolute configuration at all of their chiral centers (which, in this case, is only one). D-glyceraldehyde has an OH on the right, while L-glyceraldehyde has an OH on the left. Sugars that have their last OH on the right are D sugars; sugars that have their last OH are L sugars. Most sugars that exist in life forms are D sugars.

In the video, I depict the difference between Fischer projections (straight chain sugars) and Haworth projections (sugars in their ring forms). I also briefly mention the idea of anomers as a class of epimers, which are a specific class of diastereomers.

Diastereomers are stereoisomers that differ in at least one, but not all chiral centers.
Epimers are stereoisomers that differ at only one chiral center (they are a subclass of diastereomers).
Anomers are stereoisomers that differ at only one chiral center when that chiral center is specifically the anomeric carbon, the stereocenter that forms when a sugar forms a ring. Anomers are a subclass of epimers.

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