[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

single punch tablet press machine for tablets with logo printing powder equipment
electric single punch die stamping tablet pressing making machine hand shack pills maker equipment
Model Unit YX-P06
Max. Pressure 60kn
Max. Dia. of Tablet Φ25mm
Max. Depth of Fill 18mm
Dia. of up and down punch pole Φ10mm
Dia. of Middle Mould Φ38mm
Production Capacity 3000pc/h
Main Motor Power 0.75kw
Net Weight 145kg
Overall Size (L*W*H)
700*580*700mm
A lot of the branded vitamin tablets on the high street have unnecessary additives and supplements that you just don’t need. This press allows you to mix the vitamins and supplements that you require for your exact diet and convert them into convenient pills.Maybe you are considering setting up a small business selling vitamin, weight loss or herbal tablets. If so this is the right press for you.
Applications from single punch tablet press machine tablets making machine
a.Chemical: disinfection tablets, insect repellent films, camphor ball, detergents, fragrances, catalysts, metallurgy powder,Urotropin (for fast lighter), glass powder, ceramic powder products, charcoal powder,iron powder,art powder, sand round block, magnetic materials.
b.Food: candy tablet, seasonings block, Chicken tablets, glucose block,coffee block, chocolate small blocks etc.
c.Agriculture: Feed block, fertilizer tablets, livestock salt licking blocks;
d.Electronic Batteries: thermistor, integrated circuit components, Carboniferous brush films, quick drop-off;
e.Health Products: calcium, propolis tablets, effervescent tablets, bath salts tablets
f.Life products:Soap,dish washing plates.,bathing salt plates,candle,Camphor ball etc.
Technical Parameters of single punch tablets press machine
Model
Unit
YX-1.5
YX-5
YX-P06
Max. Pressure
kn
15
50
60
Max. Dia. of Tablet
mm
Φ14
Φ18
Φ25
Max. Depth of Fill
mm
11
15
18
Dia. of up and down punch pole
mm
Φ10
Φ10
Φ10
Dia. of Middle Mould
mm
Φ28
Φ33
Φ38
Production Capacity
pc/h
3600
2500-3800
3000
Main Motor Power
kw
0.37
0.55
0.75
Net Weight
kg
85
125
145
Overall Size (L*W*H)
mm
540*450*640
600*500*700
700*580*700
♦Features of single punch tablet pressing equipment♦
Able to make powder and granular material compressed into a circular shaped tablet
Can be widely used in pharmaceutical,chemical plants,hospitals and scientific research units
Larger Diameter Tablets up to 18mm
Adaptable,easy to use,easy maintenance,small size,light weight
It will run for hours continuously producing identical tablets time after time
Friendly Support and Prompt Services
No special forms to fill out
Up to 3500 tablets per hour can be achieved,using a maximum presser of 60KN
A powerful electric motor and can also be hand operated
♦How to Use♦
1.Before connected to electrical power,the motor should be connected to ground to ensure safety.First demolition the V-belt,connected to electrical power,starting the motor,observe motor rotation direction whether correct(Motor shaft rotation direction should be with the protective cover or hand-wheel in the opposite direction of the arrow).If the rotation in the wrong direction,another separate cable connection.Then make V-belt installed.
2.Unloading punch dies and adjustment of tablet press. a,Installation punch dies.b,Putting out the adjustment. c,The adjustment of filling the depth(tablet weight adjusted). d,Pressure adjustment. e,die demolition.
♦Item Units and Pics♦
1 X Single punch tablet press machine
Operation Manual will be sent by e-mail
1*Round die without stamp for free
Our Factory since 1992 has been manufacturing the cosmetic&food making and packaging machinery.In these field we have the experience rich enough to solve the questions encountered by our customers from both home and abroad.
For more information about penglai packaging, please visit our website at https://penglaipacking.com
SHENZHEN PENGLAI INDUSTRIAL CORPORATION LIMITED
Contact:Michael Peng Skype: penglaichina Email: penglaipacking@gmail.com whatsapp:+86-15012795261

Video abstract of original research paper “In vitro inhibition of hyaluronidase by sodium copper chlorophyllin complex and chlorophyllin analogs” published in the open access journal Clinical, Cosmetic and Investigational Dermatology by McCook et al.

Background: Inhibitors of hyaluronidase are potent agents that maintain hyaluronic acid homeostasis and may serve as anti-aging, anti-inflammatory, and anti-microbial agents. Sodium copper chlorophyllin complex is being used therapeutically as a component in anti-aging cosmeceuticals, and has been shown to have anti-hyaluronidase activity. In this study we evaluated various commercial lots of sodium copper chlorophyllin complex to identify the primary small molecule constituents, and to test various sodium copper chlorophyllin complexes and their small molecule analog compounds for hyaluronidase inhibitory activity in vitro. Ascorbate analogs were tested in combination with copper chlorophyllin complexes for potential additive or synergistic activity.
Materials and methods: For hyaluronidase activity assays, dilutions of test materials were evaluated for hydrolytic activity of hyaluronidase by precipitation of non-digested hyaluronate by measuring related turbidity at 595 nm. High-performance liquid chromatography and mass spectroscopy was used to analyze and identify the primary small molecule constituents in various old and new commercial lots of sodium copper chlorophyllin complex.
Results: The most active small molecule component of sodium copper chlorophyllin complex was disodium copper isochlorin e4, followed by oxidized disodium copper isochlorin e4. Sodium copper chlorophyllin complex and copper isochlorin e4 disodium salt had hyaluronidase inhibitory activity down to 10 μg/mL. The oxidized form of copper isochlorin e4 disodium salt had substantial hyaluronidase inhibitory activity at 100 μg/mL but not at 10 μg/mL. Ascorbate derivatives did not enhance the hyaluronidase inhibitory activity of sodium copper chlorophyllin. Copper isochlorin e4 analogs were always the dominant components of the small molecule content of the commercial lots tested; oxidized copper isochlorin e4 was found in increased concentrations in older compared to newer lots tested.
Conclusion: These results support the concept of using the hyaluronidase inhibitory activity of sodium copper chlorophyllin complex to increase the hyaluronic acid level of the dermal extracellular matrix for the improvement of the appearance of aging facial skin.

View the original paper here: https://www.dovepress.com/in-vitro-inhibition-of-hyaluronidase-by-sodium-copper-chlorophyllin-co-peer-reviewed-article-CCID