[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

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QAAFI Science Seminar

Presented by Prof. Mike Gidley
Director of Centre for Nutrition & Food Sciences at QAAFI

ABSTRACT

Plant cell walls and associated polysaccharides (a.k.a. dietary fibre) play a pivotal role in the digestion of a healthy diet, mostly as the defining structural characteristic of whole grains, fruits, nuts, and vegetables. Credible hypotheses can be constructed to link cell wall properties of these plant-based foods to reduction in risk factors for major non-communicable diseases.

The physical properties of plant cell wall polysaccharide components relevant to digestive tract functionality can be grouped into (i) bulk structuring, (ii) transport barriers, and (iii) molecular binding. Examples of each type of functionality from both in vitro and in vivo studies will be presented.

The conventional sub-division of dietary fibre into soluble and insoluble types disguises the reality that the physical form of plant cell walls in digesta is typically intermediate between the extremes of dissolved polymers and non-swollen solid particles which are often used to exemplify soluble and insoluble fibre fractions. An alternative method of categorising dietary fibres is proposed based on a combination of particle/molecule size and effective density.

About Prof. Mike Gidley

Prof. Gidley obtained a Bachelor of Science (Hons) in Chemistry, at the University of London in 1977 and went on to complete his PhD in Chemistry at the University of Cambridge in 1982.

Before establishing CNAFS in 2003 (a joint initiative between UQ and the Queensland Government), Prof. Gidley worked for Unilever Research in the United Kingdom for more than 20 years, beginning as a research scientist and culminating as the Group Leader for Plant-based Foods and Ingredients.

Prof. Gidley’s major research interest is the linking of plant molecular structures to macroscopic properties with relevance to plant-based food properties. In particular, Prof. Gidley is interested in investigating polysaccharide assemblies such as plant cell walls (as part of the Australian Research Council Centre of Excellence in Plant Cell Walls and starch granules, particularly the way these structures are assembled in nature and then disassembled during manufacturing and later during digestion.

Prof. Gidley’s field of research involves the use of spectroscopic, microscopic and materials analyses of natural materials and model systems. Insights into structure-property relationships are obtained and can then be used to provide targets for raw materials and processes with enhanced food and nutritional properties.