[Latin Name] Sambucus nigra

[Specification] Anthocyanidins15% 25% UV

[Appearance] Purple fine powder

Plant Part Used: Fruit

[Particle size] 80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is elderberry extract?]

Elderberry extract comes from the fruit of the Sambucus nigra or Black Elder, a species found in Europe, Western Asia, North Africa, and North America. Called “the medicine chest of the common people,” Elder flowers, berries, leaves, bark, and roots have all been used for centuries in traditional folk medicines.Elder fruit contains vitamins A, B and C, flavonoids, tannins, carotenoids, and amino acids. Elderberry is believed to possess therapeutic uses as an anti-inflammatory, diuretic, and immuno-stimulant.

[Function]

1. As medicine raw material: It can promote the healing of gastrointestinal ulcers; It can be used for acute and chronic hepatitis and hepatitis evocable hepatomegaly, hepatocirrhosis; promote the healing of liver function.

2. As foodstuff colorant: Widely used in cakes, beverage, candy, ice cream etc..

3. As chemical raw material for daily use: Widely used in many kinds of green medicine toothpastes and cosmetics.

Titre du document / Document title
Cytotoxic activity of Justicia spicigera is inhibited by bcl-2 proto-oncogene and induces apoptosis in a cell cycle dependent fashion
Auteur(s) / Author(s)
CACERES-CORTES J. R. (1) ; CANTU-GARZA F. A. (2) ; MENDOZA-MATA M. T. (3) ; CHAVEZ-GONZALEZ M. A. (1) ; RAMOS-MANDUJANO G. (1) ; ZAMBRANO-RAMIREZ I. R. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Research Unit of Cell Differentiation and Cancer, Faculty of Professional Studies-Zaragoza, National Autonomous University of Mexico, FES-Zaragoza, UNAM, MEXIQUE
(2) Chemistry Engineering Department, Faculty of Professional Studies-Zaragoza, National Autonomous University of Mexico, FES-Zaragoza, UNAM, ESPAGNE
(3) Pharmacology Department, Faculty of Professional Studies-Zaragoza, National Autonomous University of Mexico, FES-Zaragoza, UNAM, ESPAGNE

Résumé / Abstract
Identification of organic compounds from plants is of clinical significance because of the effect that they might have in patients with haematopoietic disorders. We studied the effect of the plant extract Justicia spicigera (Acanthaceae) in different haematopoietic cells: human leukaemic cell lines, umbilical cord blood cells, and mouse bone marrow cells. By examining colony formation and performing the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay it was shown that the plant extract of Justicia spicigera contains cytotoxic factors for leukaemic cells and has no proliferative activity on normal haematopoietic progenitor cells. Our results show that this plant extract induces apoptosis in the human leukaemia cell line TF-1, but not in the bcl-2 transfectant cell line TB-1. Similar results were obtained using a haemopoietic cell line 32D and 32DBcl2. The cultures of umbilical cord blood cells and mouse bone marrow that contain granulocyte-macrophage colony-stimulating factor (GM-CSF) do not proliferate or become terminally differentiated in the presence of the infusion of Justicia spicigera. GM-CSF that acts by abrogating programmed cell death is not sufficient to inhibit the apoptotic stimulus in TF-1 and 32D cells. Moreover mouse fibroblasts (3T3) and two cervical carcinoma cell lines CALO and INBL, undergo apoptosis in the presence of different concentrations of an infusion from the plant. Our data show that there is a strong correlation between the cytotoxic effect and cell proliferation. Together, these results indicate that the plant infusion of Justicia spicigera does not contain any haematopoietic activity, induces apoptosis inhibited by bcl-2 and is linked to cell proliferation.
Revue / Journal Title
PTR. Phytotherapy research ISSN 0951-418X
Source / Source
2001, vol. 15, no8, pp. 691-697 (24 ref.)
Langue / Language
Anglais

Editeur / Publisher
Wiley, Chichester, ROYAUME-UNI (1987) (Revue)

Mots-clés anglais / English Keywords
America ; Central America ; Spermatophyta ; Angiospermae ; Dicotyledones ; Acanthaceae ; Mexico ; Folk medicine ; Pharmacognosy ; Animal ; Human ; Apoptosis ; In vitro ; Cell proliferation ; Antineoplastic agent ; Tumor cell ; Biological activity ; Cytotoxicity ; Plant origin ; Medicinal plant ;

How to make a healthy Healthy Antioxidant Smoothie Recipe so you can take care of your wellbeing naturally & you may feel more vitality to get more out of your day and enjoy every moment.

More information about mangosteen juice: https://www.mmxgo.com/s6j
or contact cj@mangosteenwellbeing.com

I love watermelon and this is my favourite smoothie recipe.

Healthy Mangosteen Smoothie Recipe
You’ll need:
Fresh watermelon
Fresh Mint leaves
Blueberries (Frozen or fresh)
Xango Mangosteen Juice

This Antioxidant Smoothie is safe and perfect for children to drink and get lots of nutrients and vitamins – while passing the taste test.

About Xango Mangosteen juice
Harnessing mangosteen’s remarkable whole-fruit properties, XANGO Juice provides biologically active compounds and phytonutrients—including xanthones, catechins, flavonoids and proanthocyanidins—that may support respiratory health, immune health, intestinal health and joint health.