[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

Les Dethlefsen comes on Bulletproof Radio today to discuss recent discoveries about the microbiota, when you should take pre and probiotics, hacking the harmful effects that antibiotics have on our gut flora, and how a fecal transplant can save your life.

Les Dethlefsen, Ph.D., is a staff scientist at the Relman labs at Stanford. Since joining the lab in 2004, his work has been focused on the temporal dynamics of the gut microbiota. Les has an undergraduate double major in physics and molecular biology. He earned his Ph.D. in both Microbiology and Ecology/Evolutionary Biology from Michigan State. His current study, ‘Dynamics of the Human Microbiota,’ is looking for participants.

Enjoy the show!

Resources:
Pseudomonas aeruginosa – https://www.cdc.gov/hai/organisms/pseudomonas.html
Microbiota – https://en.wikipedia.org/wiki/Microbiota
Trichuris trichiura (pig whipworm eggs) – https://en.wikipedia.org/wiki/Trichuris_trichiura
Polyphenols – https://en.wikipedia.org/wiki/Polyphenol
DD-transpeptidase (Bacterial DD) – https://en.wikipedia.org/wiki/DD-transpeptidase
Firmicutes – https://en.wikipedia.org/wiki/Firmicutes
Fasting-induced adipose factor (FIAF) – https://www.ncbi.nlm.nih.gov/pubmed/16272564
Mycotoxin – https://en.wikipedia.org/wiki/Mycotoxin
Quantified Self – https://quantifiedself.com/
Probiotics – https://geni.us/3GxD
Hadza, Tanzania – https://ngm.nationalgeographic.com/2009/12/hadza/finkel-text
Polysaccharides – https://en.wikipedia.org/wiki/Polysaccharide
Caprylic acid – https://en.wikipedia.org/wiki/Caprylic_acid
Chronic low-grade inflammation – https://healthletter.mayoclinic.com/editorial/editorial.cfm/i/163/t/Buzzed%20on%20inflammation/
Glyphosate (Roundup) – https://en.wikipedia.org/wiki/Glyphosate
Fecal Transplant – https://thepowerofpoop.com/epatients/where-to-get-fecal-transplant/
Clostridium difficile (pseudomembranous colitis) – https://www.mayoclinic.org/diseases-conditions/c-difficile/basics/definition/con-20029664
Ulcerative colitis – https://www.mayoclinic.org/diseases-conditions/ulcerative-colitis/basics/definition/con-20043763
ubiome – https://ubiome.com/

Bulletproof:
Brain Octane Oil – https://www.bulletproof.com/brain-octane-oil-32-oz?utm_source=yt&utm_medium=sm&utm_campaign=pod240
MCT Oil – https://www.bulletproof.com/xct-oil-32-oz?utm_source=yt&utm_medium=sm&utm_campaign=pod240
Bulletproof Coffee Shop – https://www.bulletproofexec.com/bulletproof-coffee-shop/
Bulletproof Conference – https://bulletproofconference.com/bp-conference-2015
Moldy Movie – https://moldymovie.com/index
Bulletproof Diet Book – https://geni.us/bulletproofdietbook
Free Bulletproof Diet Roadmap – https://www.bulletproofexec.com/the-complete-illustrated-one-page-bulletproof-diet/

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