Quality Inspection for 5-HTP Manufacturer in Italy


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Quality Inspection for 5-HTP Manufacturer in Italy Detail:

[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

5-HTP1 5-HTP21

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

5-HTP31 5-HTP41

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.


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    Braggs Apple Cider Vinegar: The benefits of apple cider vinegar come from its powerful healing compounds, which include acetic acid, magnesium, probiotics, and polyphenols.
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    Weight loss/Metabolism- A study published in the Journal of Agriculture and Food Chemistry, mice fed a high-fat diet along with acetic acid — vinegar’s key component — developed up to 10% less body fat than control rodents.

    Zevia: Zevia is an all-natural zero calorie soda made without artificial sweeteners, is non-GMO, kosher, gluten-free, vegan and contains no colors, dyes or phosphoric acid. Considered all-natural, Zevia uses Stevia as a sweetener.

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    References:
    1) Acetic Acid Upregulates the Expression of Genes for Fatty Acid Oxidation Enzymes in Liver To Suppress Body Fat Accumulation – Journal of Agricultural and Food Chemistry (ACS Publications). (n.d.). Retrieved from https://pubs.acs.org/doi/abs/10.1021/jf900470c

    2) Polyphenols Can Aid Gut Health, Boost Longevity. (n.d.). Retrieved from https://www.healthline.com/health-news/food-polyphenols-boost-gut-health-and-longevity-121213#1

    3) Do Polyphenols Improve Your Gut Bacteria? (n.d.). Retrieved from https://chriskresser.com/do-polyphenols-improve-your-gut-bacteria/

    4) Effects of apple cider vinegars produced with different techniques on blood lipids in high-cholesterol-fed rats. – PubMed – NCBI. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/21561165

    5) Apple Cider Vinegar (ACV): Is it Really a Powerful Healing Tonic? – Underground Health. (n.d.). Retrieved from https://www.undergroundhealth.com/is-apple-cider-vinegar-really-a-powerful-healing-tonic-science-says-yes/

    6) The Effect of Stevia Rebaudiana on Serum Omentin and Visfatin Level in STZ-Induced Diabetic Rats (PDF Download Available). (n.d.). Retrieved from https://www.researchgate.net/publication/261289491_The_Effect_of_Stevia_Rebaudiana_on_Serum_Omentin_and_Visfatin_Level_in_STZ-Induced_Diabetic_Rats

    7) Stevioside inhibits atherosclerosis by improving insulin signaling and antioxidant defense in obese insulin-resistant mice. – PubMed – NCBI. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/20010904

    8) Sharma, N., Mogra, R., & Upadhyay, B. (2009). Effect of Stevia Extract Intervention on Lipid Profile. Retrieved from https://www.krepublishers.com/02-Journals/S-EM/EM-03-0-000-09-Web/EM-03-2-000-2009-Abst-PDF/EM-03-2-137-09-047-Sharma-N/EM-03-2-137-09-047-Sharma-N-Tt.pdf

    9) United States Patent: 6500471. (n.d.). Retrieved from https://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=/netahtml/PTO/srchnum.htm&r=1&f=G&l=50&s1=6500471.PN.&OS=PN/6500471&RS=PN/6500471

    10) EGCG extract, health benefit, side effects. (n.d.). Retrieved from https://www.raysahelian.com/egcg.html



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