[Latin Name]  Piper methyicium L.

[Specification] Kavalactones ≥30.0%

[Appearance] Yellow powder

Plant Part Used: Root

[Particle size] 80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is Kava?]

Kava, also known as piper methysticum, kava kava, and ‘awa, is a small shrub native to the islands in the South Pacific. The root and stems are made into a non-alcoholic, psychoactive beverage that has been used socially and ceremonially for hundreds of years in Hawaii, Fiji, and Tonga.

Kava is traditionally prepared by placing ground root and stem into a porous sack, submerging in water, and squeezing the juice into a large, carved, wooden bowl. Coconut half-shell cups are dipped and filled — punch bowl style. After drinking a cup or two a feeling of heightened attention combined with relaxation begins to come on. Although it is soothing, it is unlike alcohol in that thoughts remain clear. The flavor is largely inoffensive, but some find that it takes getting used to; it really depends on your preference for earthy flavors.

[Kava is Safe to Use]

The safe and effective benefits of kava to relieve symptoms of anxiety were also supported in a meta-analysis, a systematic statistical review of seven human clinical trials published in 2000 in the Journal of Clinical Psychopharmacology, and again in a similar critical review in 2001. The reviews did not find significant adverse effects related to liver toxicity.

In conclusion, the liver is affected by many substances, including prescription and non- prescription drugs, as well as alcohol, which is a major cause of liver damage. We must be aware that herbs are potent medicines, to be treated with the appropriate respect regarding potential interactions and toxicity, including to the liver. On the other hand, Kava kava’s margin of safety far surpasses that of it’s pharmaceutical equivalent.

[Function]

Kava’s can help offset a number of problems, most notably stress, anxiety, and disrupted sleep patterns. However, kava’s anxiolytic (anti-panic or anti-anxiety agent) and calming properties can offset many other stress and anxiety related ailments.

1. Kava as a Therapy for Anxiety
2. Kava May Remedy Menopausal Mood Swings

3. Weight Loss

4. Combat Premature Aging

5. Quit Smoking Aid

6. Combat pain as an analgesic

7. Insomnia

8. Depression

Found an amazing vid that shows every bit of happenings inside a cell with bright and vivid graphic presentation.

Notes:
Cell – the smallest unit of life. It takes up useful molecules and gets rid of waste molecules. It breaks down larger molecules to produce usable energy in the form of ATP molecules, where energy was stored, to synthesize other larger molecules. Big molecules are CONSTANTLY being breaking down into small molecules and the pieces used to make big molecules again, a process called ‘turnover’.

Selectin – any of a family of sugar-binding lectins that are found on the surface of cells (as endothelial cells and white blood cells) and that promote their adhesion to other cells and mediate their migration to sites of inflammation.

Leukocytes – white blood cell

Chemokine – any of a group of chemotactic cytokines that are produced by various cells (as at sites of inflammation), that are thought to provide directional cues for the movement of white blood cells (as T cells, monocytes, and neutrophils), and that include some playing a role in HIV infection because the cell surface receptors to which they bind are also used by specific strains of HIV for entry into cells.

Proteoglycan – any of a class of glycoproteins of high molecular weight that are found in the extracellular matrix of connective tissue, are made up mostly of carbohydrate consisting of various polysaccharide side chains linked to a protein, and resemble polysaccharides rather than proteins in their properties.

2 classes of receptors –
Ligand-gated ion channel
G protein-coupled receptor

Mitochondria – an organelle which break down nutrients such as glucose and provide the cell with energy to perform its function.

Membrane – defines the boundary of the cell and consists of a double layer of fatlike lipid molecules. Embedded in the membrane are a variety of protein molecules that have special functions.

Microtubule – a long strand of bundles of protein filaments arranged around a hollow core; part of the cytoskeleton and involved in transporting substances from place to place within a cell.

G-protein – a protein coupled to a metabotropic receptor. When a molecule of the neurotransmitter binds with the receptor, the receptor activates a G protein situated inside the membrane next to the receptor.

Cited:
Almon, Richard. Drugs, Stress, and Human Function. Cognella, Inc., 2013. USA

Carlson, Neil R., Foundations of Behavioral Neuroscience, 9th ed. Pearson, 2014. USA

U.S. National Library of Medicine, MedLine Plus, https://www.nlm.nih.gov/medlineplus/

(I do not own this video)