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Because of the important role of oxidative stress in skin ageing, almost every cosmetic now contains some antioxidants. The thing to look for is evidence that these products reduce the effects of UV damage (for example, by reducing the amount of damaged DNA) when used as the manufacturer intends, on the kind of skin it has been developed to protect — not just on the hides of lab mice. Be wary about believing in every marketing claim and ‘miracle in a jar’.

Ensure the products we choose have sufficiently high concentrations of their purported active ingredients (where these are known); if this isn’t stated, ensure the ‘active’ ingredients are listed in the top two-thirds of the ingredient list (preferably, higher). Ingredients listed in the final third of the label list are probably present only in very small quantities.

Only a small number of topical antioxidants have been shown in clinical trials to reduce signs of skin ageing and wrinkles. These include:
• Retinoic acid, also known as tretinoin
• Retinol and retinal (vitamin A)
• Vitamin C
• Polypodium leucotomos fern extract (P. leucotomos)
• Coenzyme Q10 (or Ubiquinione)
• Proanthocyanidins
• Polyphenols

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