The success of any toothpaste, in part, lies on its ability to eliminate pathogenic oral microflora. Fluoride dentifrices have been widely used all over the world and extensive research has established their abilities in terms of caries resistance.
The gel or mucilage from Aloe barbadensis Miller (otherwise known as aloe vera) is a convenient homegrown remedy that can be used both as a moisturizing agent and for treating minor burns and skin abrasions. Aloe vera is a cactus-like plant that actually is part of the lily family. There are more than 300 varieties of the aloe plant but the Aloe barbadensis variety exhibits the best medicinal properties.
Modern use of aloe vera was first documented in the 1930s to heal radiation burns. Aloe vera juice taken internally has been shown to have various beneficial effects on the body.
The efficacy of Aloe barbadensis Miller increases when the plant is harvested after three years of growth but its nutritive potency decreases after 12 years of growth. Aloe gel will lose its complete potency if it is exposed to sunlight for more than two hours, as it is easily oxidized; consequently, it is necessary to stabilize it under pharmaceutical standards for ready use and longer shelf life. Non-profit organizations like the International Aloe Science Council have set standards for aloe vera approval and give their seal of quality for aloe products. Such products are more beneficial, since the seal is given to only those products with established therapeutic benefits.
This in vitro evaluation compared the antimicrobial activity of an aloe vera tooth gel and two commercially popular, locally available toothpastes. These toothpastes were tested against seven pathogenic microorganisms that frequently dominate the oral microbiota. The results are intended to show the relative antimicrobial effectiveness of each dentifrice against each particular species.

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