UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Lec 15. Introduction to Chemical Biology — Glycobiology & Polyketides — Part 1
View the complete course: https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html
Instructor: Gregory Weiss, Ph.D.

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Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Introduction to Chemical Biology (Chem 128) is part of OpenChem: https://ocw.uci.edu/collections/open_chemistry.html
This video is part of a 18-lecture undergraduate-level course titled “Introduction to Chemical Biology” taught at UC Irvine by Professor Gregory Weiss.

Recorded March 5, 2013.

Index of Topics:
0:00:19 Carbohydrates
0:03:15 Glycosylated Proteins
0:07:25 Extending Oligosaccharides one Monomer at a Time
0:08:26 More Knee Join Oligosacchardies
0:10:25 Snot and Mucus: Anionic Polysaccharides
0:13:21 N-Linked Glycosides: Added as Complex Oligosaccharides
0:22:56 What is the Function of Glycosylation?
0:25:37 Cell Culture Production of Proteins
0:27:54 Glucoronidation Used to Designate Small Molecules for Excretion
0:29:49 Glucose Homeostasis
0:31:39 Non-Enzymatic Glycosylation
0:35:29 Sweetners: Tase Good for the Calories
0:41:00 Terpenes and Polyketides
0:45:09 Nature Prefers Thioesters for the Claisen
0:48:06 Rapid Exchange of Thioesters
0:49:28 Fatty Acid Synthesis by Polyketide

Required attribution: Weiss, Gregory Introduction to Chemical Biology 128 (UCI OpenCourseWare: University of California, Irvine), https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html. [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License (https://creativecommons.org/licenses/by-sa/3.0/us/deed.en_US).