UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Lec 16. Introduction to Chemical Biology — Glycobiology & Polyketides — Part 2
View the complete course: https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html
Instructor: Gregory Weiss, Ph.D.

License: Creative Commons BY-NC-SA
Terms of Use: https://ocw.uci.edu/info.
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Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Introduction to Chemical Biology (Chem 128) is part of OpenChem: https://ocw.uci.edu/collections/open_chemistry.html
This video is part of a 18-lecture undergraduate-level course titled “Introduction to Chemical Biology” taught at UC Irvine by Professor Gregory Weiss.

Recorded March 5, 2013.

Index of Topics:
0:00:33 Polysaccharides
0:08:45 Fatty Acid Synthase: Paradigm for a Polyketide Synthesis Machine
0:10:58 Plasma Membrane = Lipid Barrier
0:13:44 Hydrolysis of LIpids in Cell Signaling
0:15:26 Prostaglandin Signaling to Coordinate Cell Response
0:16:15 Leukotrienes Mediate Inflammatory Response
0:19:09 Shutting Down the Prostaglandin Pathway at its Start
0:23:39 Converting Fats into Soaps
0:25:54 Diversifying Products from Polyketide Synthases
0:39:54 Fatty Acid Synthase (FAS) Has a Circular Assembly Line
0:44:18 Terpenes: Built from Isoprene (5C) Units
0:56:18 Inhibition of Cholesterol Synthesis
0:57:48 Cyclization of Straight-Chain Precursors by Enzymes

Required attribution: Weiss, Gregory Introduction to Chemical Biology 128 (UCI OpenCourseWare: University of California, Irvine), https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html. [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License (https://creativecommons.org/licenses/by-sa/3.0/us/deed.en_US).