Table of Contents:
00:00 L1.1: Cells By the Numbers
00:28 In this lecture …
01:02 Why Start with the Numbers?
01:59 Why Start with the Numbers?
02:28 Size & Volume
03:30 E. coli: a frame of reference
03:55 Mass
04:52 Composition
06:38 Mass of 1 Cell Changes with Time
07:56 # of molecules / cell
09:37 Concentration
10:33 Time
13:00 Time
14:56 Manufacturing – Raw Materials & Costs
16:58 Energy Costs
17:55 Pressure & Forces
20:14 Resources …
21:11 Coming up…

This video is part of the nanoHUB-U course “Biological Engineering: Cellular Design Principles” currently offered on nanoHUB-U (https://nanohub.org/courses/biod) or on EdX (https://www.edx.org/course/biological-engineering-cellular-design-purduex-nano545x)

Cellular Design Principles is a five week course that explores the design principles underlying mechanisms of cellular and biomolecular functions such as cell architecture, energy storage and conversion, sensing and signaling, communication, time keeping, molecular synthesis, memory, and motility. Emphasis will be placed on the chemical, physical, and mathematical features that determine the performance of the biological device. Topics cover both cellular/biochemical processes and molecular/genetic circuits. Examples are presented from reverse engineering of natural systems and design of new synthetic systems.