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Polyphenols are chemicals found in many plants. Polyphenols are usually antioxidants that can protect cells from oxidative damage caused by free radicals. Polyphenols include tannins, lignins, and flavonoids. Many polyphenols have anti-obesity activities and are beneficial for weight loss. Aging and obesity may lead to inflammatory and oxidative conditions. Inflammation and oxidative stress are also important pathological factors in obesity-related diseases such as diabetes, fatty liver, cardiovascular diseases, and cancer. Polyphenol extracts from fruits and herbs such as apples and green tea can inhibit inflammation, lower blood cholesterol and glucose levels, and reduce risks of heart diseases. These natural antioxidants can be used as dietary supplements without evident adverse effects. The latest discoveries and studies of cellular and molecular mechanisms of such polyphenols suggest that they can be potential agents for the treatment of obesity and associated diseases. Excerpts: recent studies have elucidated the possible effects of for weight loss. For example, has been found to reduce dietary lipid absorption in humans Supplementation with stopped diet-induced obesity. treatment also showed a positive effect on improving mood. Short-term treatment has been found to reverse preexisting high-fat-induced metabolic pathologies in obese subjects. In the long-term, treatment can inhibit the development of obesity, symptoms associated with the metabolic syndrome, and fatty liver. the tested group took the supplement for twelve weeks. The study found that ingestion of led to the reduction of total cholesterol and low-density lipoprotein (ldl)-cholesterol levels. The supplement also improved the visceral fat area . No adverse reactions were observed. these studies demonstrate that may help regulate fat metabolism, protect against inflammation, and be beneficial for obese and aging problems. such studies suggest that has properties as a potent antioxidant