[Latin Name] Andrographis paniculata(Burm.f.)Nees

[Plant Source] Whole herb

[Specification] Andrographolides 10%-98% HPLC

[Appearance] White powder

Plant Part Used: Herb

[Particle size] 80Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is Andrographis?]

Andrographis paniculata is a bitter tasting annual plant, referred to as the “King of Bitters.” It has white-purple flowers and it is native to Asia and India where it has been valued for centuries for its numerous medicinal benefits. Over the past decade, andrographis has become popular in America where it is often used alone and in combination with other herbs for a variety of health purposes.

[How does it work?]

According to Memorial Sloan-Kettering Cancer Center, the active ingredient in andrographis is andrographolides. Due to the andrographolides, andrographis has potent anti-inflammatory and antimalarial properties. It also has antimicrobial properties, meaning it can help to fight off and prevent infections from harmful microorganisms such as viruses, bacteria and fungi. In addition, andrographis is a powerful antioxidant and it can help to prevent free radical induced damage to your cells and DNA

[Function]

Cold and Flu

Scientists have discovered that andrographis helps to boost the immune system by stimulating the body’s production of antibodies and macrophages, which are large white blood cells that scavenge harmful microorganisms. It is taken for both the prevention and treatment of the common cold, and it is often referred to as Indian echinacea. It might help lessen the severity of cold symptoms such as sleeplessness, fever, nasal drainage and sore throat.

Cancer, Viral Infections and Heart Health

Andrographis may also help to prevent and treat cancer, and preliminary studies done in test tubes found that extracts of andrographis help to treat stomach, skin, prostate and breast cancer. Due to the herb’s antiviral properties, andrographis is used to treat herpes and it is also currently being studied as a treatment for Aids and HIV as well. Andrographis also promotes heart health and can help to prevent the formation of blood clots as well as to dissolve already formed blood clots. In addition, the herb relaxes smooth muscles in the walls of blood vessels and thereby helps to reduce high blood pressure.

Additional Benefits

Andrographis is used to promote gallbladder and digestive health. It also helps to support and strengthen the liver and it is used in combination with other herbs in several Ayurvedic formulations to treat liver disorders. Finally, andrographis extracts taken orally have been found to help neutralize the poisonous effects of snake venom.

Dosage and Precautions

The therapeutic dose of andrographis is 400 mg, twice daily, for up to 10 days. Although andrographis is considered safe in humans, the NYU Langone Medical Center warns that animal studies suggest that it may impair fertility. Andrographis may cause unwanted side effects such as headaches, fatigue, allergic reactions, nausea, diarrhea, altered taste and pain in the lymph nodes. It may also interact with certain medications and as with any supplement you should consult your health care practitioner before taking the herb.

https://www.healthdesigns.com/mhp-no-bomb-96-capsules?code=13512961
Revolutionary KNO3 Nitrate-NO Technology. Maximum Performance Formula. Pre and Post Workout Beneftis: Sustain Massive Muscle Pumps, Increase Muscle Size & Strength. Increase Energy & Endurance, Reduce Lactic Acid & Improve Recovery, Enhance Fat Burning. Clinically Tested Nitric Oxide Maximum Performance Formula: No-Bomb represents the biggest supplement breakthrough ever for anyone who engages in weight training in an effort to increase muscle size, strength and endurance, while improveing performance and body composition. Never before has one formula been able to deliver all of these clinically supported benefits. MHP scientist have raised the bar on clinically tested efficacy in the development of No-Bomb, the first ever formula to use a Sigma-tau certified full clinical dose of the patented biochemically modified pharmaceutical compound GlycoCarn. At the clinically dosed 4.5 grams, this compound has been shown to be far superior to Arginine and AAKG is boosting nitric oxide levels to help trigger far greater pumps and muscle growth. In addition its superior NO-boosting effects, GlycoCarn also has many other benefits including triggering lactic acid for increased endurance, powerful antioxidant properties for improved recovery and increase fatty acid metabolism for increase energy and fat burning. No-Bomb goes even further to set itself apart from all other NO formulas by introducing another major breakthrough in nitric oxide with its KNO3 Nitrite-NO Technology. This is a new development that utilizes bioactive nitrates and nitrites. The revolutionary KNO3 Nitrite NO-Technology has been shown to increase vasodilation independent of nitric oxide. Furthermore, KNO3 Nitrite-NO Technology utilizes a newly discovered nitric oxide pathway and is recycled into nitric oxide to provide even greater vasodilation and muscle pumps. Additionally, KNO3 Nitrite-NO Technology has been shown to sustain muscle pumps far greater and longer than nitric oxide. NO-Bomb’s revolutionary dual-action clinically dosed GlycoCarn/KNO3 Nitrite-NO Technology combination products powerful synergistic nitric oxide effects far beyond anything you have even taken before. Spare no expense and take your pumps and performance to a new level with the most advanced clinically researched formula ever created! The New Age of Nitric Oxide for the Guaranteed Best Pump Ever! Welcome to the new age in nitric oxide for the greatest pumps and best workouts of your life! When taken pre-workout at the clinical dose, No-Bomb’s revolutionary formula is certain to maximize your workouts and deliver amazing muscle pumps. No-Bomb also provides numerous post-workout benefits including improved recovery and delivery of critical nutrients to muscle tissue to support muscle growth. Why No-Bomb is Superior! Based on the latest scientific research, No-Bomb’s GlycoCarn/KNO3 Nitrite-NO Technology introduces a new and better approach for boosting nitric oxide levels. This groundbreaking formula overcomes the deficiencies of the Arginine-NOS pathyway to ensure maximum muscle pumps. By utilizing this newly discovered Nitrate-Nitrite NO pathway, you can ensure the continuous product of nitric oxide. Additionally, this pathway has been shown to increase the blood’s oxygen carrying capacity, which is critical for optimizing workouts and athletic performance. MHP is totally confident in No-Bomb’s nitric oxide superiority. Use it and you’ll experience the greatest muscle-building workouts and most awesome pumps ever! KNO3 Nitrite-NO Technology And NOSA (Nitric Oxide Sustaining Agents): K-NOx (Beta Vulgaris Extract (Root)), Grape Seed Extract (95% Proanthocyanidins), Pine Bark Extract (85% Proanthocyanidins, Butea Superba (Root), Glycyrrhiza Uralensis (Root), Forsythia Suspensa Extract (Fruit), AstaReal (Astaxanthin) And Schizonepeta Tenuifolia Extract (Aerial Parts)

UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Lec 16. Introduction to Chemical Biology — Glycobiology & Polyketides — Part 2
View the complete course: https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html
Instructor: Gregory Weiss, Ph.D.

License: Creative Commons BY-NC-SA
Terms of Use: https://ocw.uci.edu/info.
More courses at https://ocw.uci.edu

Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Introduction to Chemical Biology (Chem 128) is part of OpenChem: https://ocw.uci.edu/collections/open_chemistry.html
This video is part of a 18-lecture undergraduate-level course titled “Introduction to Chemical Biology” taught at UC Irvine by Professor Gregory Weiss.

Recorded March 5, 2013.

Index of Topics:
0:00:33 Polysaccharides
0:08:45 Fatty Acid Synthase: Paradigm for a Polyketide Synthesis Machine
0:10:58 Plasma Membrane = Lipid Barrier
0:13:44 Hydrolysis of LIpids in Cell Signaling
0:15:26 Prostaglandin Signaling to Coordinate Cell Response
0:16:15 Leukotrienes Mediate Inflammatory Response
0:19:09 Shutting Down the Prostaglandin Pathway at its Start
0:23:39 Converting Fats into Soaps
0:25:54 Diversifying Products from Polyketide Synthases
0:39:54 Fatty Acid Synthase (FAS) Has a Circular Assembly Line
0:44:18 Terpenes: Built from Isoprene (5C) Units
0:56:18 Inhibition of Cholesterol Synthesis
0:57:48 Cyclization of Straight-Chain Precursors by Enzymes

Required attribution: Weiss, Gregory Introduction to Chemical Biology 128 (UCI OpenCourseWare: University of California, Irvine), https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html. [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License (https://creativecommons.org/licenses/by-sa/3.0/us/deed.en_US).