15 Years Manufacturer Phytosterol Wholesale to Brisbane
15 Years Manufacturer Phytosterol Wholesale to Brisbane Detail:
[Latin Name] Glycine max(L.) Mere
[Specification] 90%; 95%
[Appearance] White powder
[Melting point] 134-142℃
[Particle size] 80Mesh
[Loss on drying] ≤2.0%
[Heavy Metal] ≤10PPM
[Storage] Store in cool & dry area, keep away from the direct light and heat.
[Shelf life] 24 Months
[Package] Packed in paper-drums and two plastic-bags inside.
[Net weight] 25kgs/drum
[What is Phytosterol?]
Phytosterols are compounds found in plants that resemble cholesterol. The National Institutes of Heath report that there are over 200 different phytosterols, and the highest concentrations of phytosterols are found naturally in vegetable oils, beans and nuts. Their benefits are so recognized that foods are being fortified with phytosterols. At the supermarket, you may see orange juice or margarine advertising phytosterol contents. After reviewing the health benefits, you may want to add phytosterol-rich foods to your diet.
[Benefits]
Cholesterol-Lowering Benefits
The most well-known, and scientifically proven, benefit of phytosterols is their ability to help lower cholesterol. A phytosterol is a plant compound that is similar to cholesterol. A study in the 2002 issue of “Annual Review of Nutrition” explains that phytosterols actually compete for absorption with cholesterol in the digestive tract. While they prevent the absorption of regular dietary cholesterol, they themselves are not easily absorbed, which leads to a total lower cholesterol level. The cholesterol-lowering benefit does not end with a good number on your blood work report. Having lower cholesterol leads to other benefits, such as a reduced risk for heart disease, stroke and heart attacks.
Cancer Protection Benefits
Phytosterols have also been found to help protect against the development of cancer. The July 2009 issue of the” European Journal of Clinical Nutrition” offers encouraging news in the fight against cancer. Researchers at the University of Manitoba in Canada report that there is evidence that phytosterols help prevent ovarian, breast, stomach and lung cancer. Phytosterols do this by preventing the production of cancer cells, stopping the growth and spread of cells that are already in existence and actually encouraging the death of cancer cells. Their high anti-oxidant levels are believed to be one way phytosterols help fight cancer. An anti-oxidant is a compound that fights free radical damage, which is negative effects on the body produced by cells that are unhealthy.
Skin Protection Benefits
A lesser known benefit of phytosterols involves skin care. One of the contributing factors in the aging of the skin is the breakdown and loss of collagen — the main component in connective skin tissue — and sun exposure is a major contributor to the problem. As the body ages, it is not able to produce collagen as it once did. The German medical journal “Der Hautarzt” reports a study in which various topical preparations were tested on skin for 10 days. The topical treatment that showed anti-aging benefits to the skin was the one that contained phytosterols and other natural fats. It is reported that phytosterols not only stopped the slow-down of collagen production that can be caused by the sun, it actually encouraged new collagen production.
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Title: Cyanidin-3-O-glucoside ameliorates lipid and glucose accumulation in C57BL/6J mice via activation of PPAR-α and AMPK?
3rdInternational Conference and Exhibition on Nutrition & Food Sciences
September 23-25, 2014 Valencia , Spain
OMICS International: https://conferenceseries.com/
Pharmaceutical Conferences: https://pharmaceuticalconferences.com
Global OMICS open access Journals: https://omicsonline.org
Global Medical Conferences: https://conferenceseries.com
Global Cancer Conferences: https://cancersummit.org
Global Diabetes Conferences: https://diabetesexpo.com
Global Dental Conferences: https://dentalcongress.com
Global Nursing Conferences: https://nursingconference.com
Abstract
Cyanidin-3-O-glucoside (C3G) is an anthocyanidin abundant in fruits and vegetables that exhibits potent activities in energy metabolism; however, molecular target(s) and the mode of actions of C3G have been elusive. Surface plasmon resonance and time-resolved fluorescence resonance energy transfer analyses revealed that C3G directly interacted with PPARα ligand-binding domain, thus the C3G induced hepatic fatty acid oxidation and ketogenesis regulating PPARα responsive genes. C3G also bound directly to the α1 subunit of AMPK in cell-free kinase assay, phosphorylated ACC1, decreased hepatic malonyl- CoA concentration, thus reduced hepatic fatty acid synthesis. In high-fat-diet fed C57BL/6J mice orally administrated with C3G for 8 weeks, hepatic and plasma triglycerides were significantly reduced due to the combined effects of PPARα and AMPK activation. Insulin resistance and glucose tolerance were significantly improved with reduction in hepatic gluconeogenesis in C3G mice compared with those of controls. The AMPK activation by C3G led to the phosphorylation inhibition of FoxO1 and CREB to suppress the expressions of key genes in hepatic gluconeogenesis. Body fat accumulation was reduced in C3G fed mice with induction of thermogenic gene expressions in brown adipocytes and energy expenditure was significantly increased in mice fed C3G. Hepatic autophagy pathway was significantly activated in C3G livers, via activation AMPK-mTORsignaling axis and PPARα activation. Autophagy activation may contribute to lowering lipid accumulation in the liver. Collectively, these demonstrate that C3G in diet has profound metabolic roles in regulating lipid metabolism and insulin resistance via activation of both PPARα and AMPK.
Biography
YaoyaoJia earned her Degree of Doctor of Philosophy from Food Science and Technology Department of Biotechnology Graduate School of Korea University. Her research is mainly focus on effects of natural compounds in cellular lipid metabolism and regulation of PPAR activity.
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