[Dzina lachilatini]Hypericum perforatum

[Magwero a Zomera] Kuchokera ku China

[Maonekedwe] ufa wabwino wa Brown

[Zofotokozera] 0.3% Hypericin

[Kukula kwa kachigawo] 80 Mesh

[Kutaya pakuyanika] ≤5.0%

[Chitsulo Cholemera] ≤10PPM

[Zotsalira za mankhwala] EC396-2005, USP 34, EP 8.0, FDA

[Kusungirako] Sungani pamalo ozizira komanso owuma, khalani kutali ndi kuwala kwachindunji ndi kutentha.

[Phukusi] Odzaza ndi mapepala-ng'oma ndi matumba awiri apulasitiki mkati.

[Kodi St. John's wort ndi chiyani]

John's wort (Hypericum perforatum) ali ndi mbiri yakale yogwiritsidwa ntchito ngati mankhwala kuyambira ku Greece wakale, komwe ankagwiritsidwa ntchito pa matenda osiyanasiyana, kuphatikizapo matenda osiyanasiyana a mitsempha. John's wort alinso ndi antibacterial, antioxidant, ndi antiviral properties. Chifukwa cha mphamvu yake yotsutsa-kutupa, yagwiritsidwa ntchito pakhungu kuti ichiritse mabala ndi kutentha. John's wort ndi imodzi mwa mankhwala azitsamba omwe amagulidwa kwambiri ku United States.

M’zaka zaposachedwapa, wort wa St. Kafukufuku wambiri amasonyeza kuti St. John's wort ingathandize kuchiza kuvutika maganizo kwapang'onopang'ono, ndipo imakhala ndi zotsatira zochepa kusiyana ndi mankhwala ena ambiri omwe amaperekedwa ndi dokotala.

[Ntchito]

1. Anti-depressive ndi sedative katundu;

2. Njira yabwino yothetsera dongosolo lamanjenje, kukangana kopumula, nkhawa ndi kulimbikitsa mzimu;

3. Anti-kutupa

4. Kupititsa patsogolo kayendedwe ka capillary

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Mkaka nthula (Silybum marianum) ndi zitsamba ku Europe, ndi zaka zoposa 2000 anthu kumwa, ntchito chikhalidwe matenda a chiwindi, koma kwenikweni zothandiza? Dziwani apa!

Zolemba za Sayansi:

Bosch-Barrera, J., & Menendez, JA (2015). Silibinin ndi STAT3: Njira yachilengedwe yolondolera zinthu zolembera zochizira khansa. Ndemanga za Chithandizo cha Khansa, 41 (6), 540-546. - https://www.ncbi.nlm.nih.gov/pubmed/25944486

Bosch-Barrera, J., Sais, E., Cañete, N., Morocco, J., Cuyàs, E., Izquierdo, A., … Menendez, JA (2016). Kuyankha kwa metastasis yaubongo kuchokera kwa odwala khansa ya m'mapapo kupita ku chinthu chapakamwa chopatsa thanzi chokhala ndi silibinin. Oncotarget, 7(22), 32006–32014. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077992/pdf/oncotarget-07-32006.pdf

Freedman, ND, Curto, TM, Morishima, C., Seeff, LB, Goodman, ZD, Wright, EC, … Gulu Loyeserera la HALT-C. (2011).Silymarin kugwiritsa ntchito ndi kupitilira kwa matenda a chiwindi mu mayeso a HALT-C. Alimentary Pharmacology & Therapeutics, 33 (1), 127-137. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490214/pdf/nihms415758.pdf

Freitag, AF, Cardia, GFE, da Rocha, BA, Aguiar, RP, Silva-Comar, FM de S., Spironello, RA, … Cuman, RKN (2015). Hepatoprotective zotsatira za silymarin (Silybum marianum) pa hepatotoxicity yoyambitsidwa ndi acetaminophen mu makoswe omwe amawotcha kwambiri. Umboni Wothandizira Mankhwala Othandizira ndi Njira Zina : eCAM, 2015, 538317. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363982/pdf/ECAM2015-538317.pdf

Hong, M., Li, S., Tan, HY, Wang, N., Tsao, S.-W., & Feng, Y. (2015). Mkhalidwe wamakono wamankhwala azitsamba pamankhwala osatha a chiwindi: The biological effects, molecular targets and futures. International Journal of Molecular Sciences, 16 (12), 28705-28745. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691073/pdf/ijms-16-26126.pdf

Kawaguchi-Suzuki, M., Frye, RF, Zhu, H.-J., Brinda, BJ, Chavin, KD, Bernstein, HJ, & Markowitz, JS (2014). Zotsatira za nthula ya mkaka (Silybum marianum) pa ntchito ya cytochrome P450 ya anthu. Mankhwala a Metabolism ndi Makhalidwe, 42 (10), 1611-1616. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164972/pdf/dmd.114.057232.pdf

Kumar, R., Deep, G., & Agarwal, R. (2015). Chidule cha ultraviolet B radiation-induced skin cancer chemoprevention by silibinin. Malipoti Amakono a Pharmacology, 1(3), 206-215. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471873/pdf/nihms-672250.pdf

Lazzeroni, M., Guerrieri-Gonzaga, A., Gandini, S., Johansson, H., Serrano, D., Cazzaniga, M., … & Bonanni, B. (2016). Kufufuza kwapang'onopang'ono kwa oral silybin-phosphatidylcholine mwa odwala omwe ali ndi khansa ya m'mawere oyambirira. Kafukufuku Woteteza Khansa, 9 (1), 89-95. - https://cancerpreventionresearch.aacrjournals.org/content/canprevres/9/1/89.full.pdf

Schrieber, SJ, Hawke, RL, Wen, Z., Smith, PC, Reddy, KR, Wahed, AS, … Fried, MW (2011). Kusiyana kwa kachitidwe ka silymarin pakati pa odwala omwe ali ndi matenda a chiwindi osaledzeretsa komanso matenda a hepatitis C. Drug Metabolism and Disposition, 39 (12), 2182-2190. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226378/pdf/zdd2182.pdf

Surai, PF (2015).Silymarin monga antioxidant zachilengedwe: Chidule cha umboni waposachedwa ndi momwe amawonera. Antioxidants, 4 (1), 204-247. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665566/
Yang, Z., Zhuang, L., Lu, Y., Xu, Q., & Chen, X. (2014). Zotsatira ndi kulolerana kwa silymarin (mkaka wamkaka) mwa odwala matenda a hepatitis C omwe ali ndi kachilombo ka HIV: Meta-analysis of randomized controlled trials. BioMed Research International, 2014, 941085. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163440/pdf/BMRI2014-941085.pdf

Wu, J.-P., Tsai, C.-C., Yeh, Y.-L., Lin, Y.-M., Lin, C.-C., Day, CH, … Huang, C.- Y. (2015).Silymarin imathandizira kusinthika kwa chiwindi pambuyo pa hepatectomy yochepa. Umboni Wothandizira Mankhwala Othandizira ndi Njira Zina : eCAM, 2015, 603529. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539063/pdf/ECAM2015-603529.pdf

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