[Dzina lachilatini]Huperzia serratum

[Source] Huperziceae therere lonse laku China

[Maonekedwe]Burawuni mpaka oyera

[Zopangira]Huperzine A

[Matchulidwe]Huperzine A 1% - 5%, HPLC

[Kusungunuka] Kusungunuka mu chloroform, methanol, ethanol, kusungunuka pang'ono m'madzi

[Kukula kwa kachigawo] 80 Mesh

[Kutaya pakuyanika] ≤5.0%

[Chitsulo Cholemera] ≤10PPM

[Zotsalira za mankhwala] EC396-2005, USP 34, EP 8.0, FDA

[Kusungirako] Sungani pamalo ozizira komanso owuma, khalani kutali ndi kuwala kwachindunji ndi kutentha.

[Moyo wa alumali] Miyezi 24

[Phukusi] Odzaza ndi mapepala-ng'oma ndi matumba awiri apulasitiki mkati.

[Huperzine A ndi chiyani]

Huperzia ndi mtundu wa moss womwe umamera ku China. Zimagwirizana ndi mosses zamakalabu (banja la Lycopodiaceae) ndipo akatswiri ena amadzimadzi amadziwika kuti Lycopodium serratum. Moss yonse yokonzedwa idagwiritsidwa ntchito mwachikhalidwe. Kukonzekera kwa zitsamba zamakono kumagwiritsa ntchito alkaloid yokhayokha yomwe imadziwika kuti huperzine A. Huperzine A ndi alkaloid yomwe imapezeka mu huperzia yomwe yanenedwa kuti imalepheretsa kuwonongeka kwa acetylcholine, chinthu chofunikira kwambiri chomwe chimafunika ndi dongosolo lamanjenje kuti lipereke chidziwitso kuchokera ku selo kupita ku selo. Kafukufuku wa zinyama wasonyeza kuti mphamvu ya huperzine A yosunga acetylcholine ingakhale yaikulu kuposa ya mankhwala ena olembedwa ndi dokotala. Kutayika kwa ntchito ya acetylcholine ndi gawo loyamba la zovuta zingapo za ubongo, kuphatikizapo matenda a Alzheimer's. Huperzine A itha kukhalanso ndi chitetezo paminyewa yaubongo, ndikuwonjezera kuthekera kwake kothandizira kuchepetsa zizindikiro za zovuta zina zaubongo.

[Ntchito] Yogwiritsidwa ntchito m'mankhwala osagwiritsidwa ntchito masiku onse, huperzine A yapezedwa kuti imakhala ngati cholinesterase inhibitor, mtundu wa mankhwala omwe amagwiritsidwa ntchito poletsa kusweka kwa acetylcholine (mankhwala ofunikira pophunzira ndi kukumbukira).

Osagwiritsidwa ntchito ngati chithandizo cha matenda a Alzheimer's, huperzine A imanenedwanso kuti imathandizira kuphunzira ndi kukumbukira komanso kuteteza ku kuchepa kwa chidziwitso chokhudzana ndi ukalamba.

Kuonjezera apo, huperzine A nthawi zina amagwiritsidwa ntchito kulimbikitsa mphamvu, kuonjezera tcheru, ndi kuthandizira kuchiza myasthenia gravis (matenda a autoimmune omwe amakhudza minofu).

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Usiku wa Hydr8 ndi wolemera, wopatsa mphamvu kwambiri, wothira moisturizer usiku wonseResveratrolkwa moyo wautali wa ma cell ndikubwezeretsanso Beta-Glucan.

Zoyenera pakhungu lamitundu yonse. Zoyenera kugwiritsidwa ntchito ndi Medik8 Retinol 3 TR.

Medik8 ntchito mphamvu akatswiriResveratrolyochokera ku Japan Giant Knotweed yomwe imakhala yokhazikika kwambiri kuposa magwero a khungu la mphesa.Resveratrol ndi kalasi yatsopano yopangira, yotchedwa Silent Information Regulator, imalimbikitsa moyo wautali wa maselo ndikuthandizira kuoneka bwino kwa khungu lotopa usiku wonse. Beta-Glucan , yomwe nthawi zambiri imachokera ku bowa wa ku Japan, ndi chinthu chachiwiri champhamvu kwambiri mu Hydr8 Night. Beta-Glucanimathandiza kuthandizira kukonzanso kwachilengedwe kwa khungu ndipo ndi yabwino pakukonzanso khungu lausiku.

Pamodzi ndi zochotsa zoziziritsa kukhosi, kuphatikiza Valerian ndi Passionflower, Hydr8 Night ndiye tanthauzo latsopano la 'kugona kokongola'.

Resveratrol ndi phytoalexin, mtundu wa maantibayotiki opangidwa mwachibadwa ndi zomera zomwe zimagwidwa ndi tizilombo toyambitsa matenda monga mabakiteriya kapena bowa, komanso kuwonetseredwa kwa UV kapena kuvulala kwakuthupi. Ili ndi mphamvu ya antioxidant, anti-inflammatory and anti-carcinogenic properties ndipo imadziwika kwambiri chifukwa cha mphamvu yake yowonjezera moyo wautali wa ma cell. Maziko a zonenazi adamangidwa pa zomwe adapeza David Sinclair, PhD, ku Harvard University, yemwe adatsimikiza kuti resveratrol imakhudza ntchito ya banja la sirtuin gene, lomwe limadziwikanso kuti "majini amoyo wautali" - gulu la jini 7. kugwirizana ndi ukalamba. Sirtuin nthawi zambiri amatchedwa 'woteteza maselo' chifukwa amathandizira ma cell kuti adzikonzere okha akatsala pang'ono kuwonongedwa. Selo likazengereza pakati pa kulimbana kapena kugonja, sirtuin amalowerera ndikulikopa kuti limenyane ndi kudzikonza lokha. Popanda sirtuin, selo likadafa ndipo maselo amafa, mibadwo imodzi.

Resveratrol mwachilengedwe amapezeka mumitundu iwiri ya isomer - cis ndi trans. Mwa awiriwa, ndi trans isomer yomwe yawonetsedwa m'maphunziro ambiri kuti ndiyomwe imathandizira kwambiri komanso yopindulitsa ya resveratrol. Medik8 imangogwiritsa ntchito resveratrol yolondola yochokera ku Japanese Knotweed - chomera cholimba, chokhazikika cha herbaceous chomwe nthawi zambiri chimawonedwa ngati gwero lochulukirapo komanso lodalirika la resveratrol.