[Dzina lachilatini]Huperzia serratum

[Source] Huperziceae therere lonse laku China

[Maonekedwe]Wofiirira mpaka woyera

[Zopangira]Huperzine A

[Matchulidwe]Huperzine A 1% - 5%, HPLC

[Kusungunuka] Kusungunuka mu chloroform, methanol, ethanol, kusungunuka pang'ono m'madzi

[Kukula kwa kachigawo] 80 Mesh

[Kutaya pakuyanika] ≤5.0%

[Chitsulo Cholemera] ≤10PPM

[Zotsalira za mankhwala] EC396-2005, USP 34, EP 8.0, FDA

[Kusungirako] Sungani pamalo ozizira komanso owuma, khalani kutali ndi kuwala kwachindunji ndi kutentha.

[Moyo wa alumali] Miyezi 24

[Phukusi] Odzaza ndi mapepala-ng'oma ndi matumba awiri apulasitiki mkati.

[Huperzine A ndi chiyani?

Huperzia ndi mtundu wa moss womwe umamera ku China. Zimagwirizana ndi mosses zamakalabu (banja la Lycopodiaceae) ndipo akatswiri ena amadzimadzi amadziwika kuti Lycopodium serratum. Moss yonse yokonzedwa idagwiritsidwa ntchito mwamwambo. Kukonzekera kwa zitsamba zamakono kumagwiritsa ntchito alkaloid yokhayokha yomwe imadziwika kuti huperzine A. Huperzine A ndi alkaloid yomwe imapezeka mu huperzia yomwe yanenedwa kuti imalepheretsa kuwonongeka kwa acetylcholine, chinthu chofunikira kwambiri chomwe chimafunika ndi dongosolo lamanjenje kuti lipereke chidziwitso kuchokera ku selo kupita ku selo. Kafukufuku wa zinyama wasonyeza kuti mphamvu ya huperzine A yosunga acetylcholine ingakhale yaikulu kuposa ya mankhwala ena olembedwa ndi dokotala. Kutayika kwa ntchito ya acetylcholine ndi gawo loyamba la zovuta zingapo za ubongo, kuphatikizapo matenda a Alzheimer's. Huperzine A itha kukhalanso ndi chitetezo paminyewa yaubongo, ndikuwonjezera kuthekera kwake kothandizira kuchepetsa zizindikiro za zovuta zina zaubongo.

[Ntchito] Yogwiritsidwa ntchito m'mankhwala osagwiritsidwa ntchito masiku onse, huperzine A yapezedwa kuti imakhala ngati cholinesterase inhibitor, mtundu wa mankhwala omwe amagwiritsidwa ntchito poletsa kusweka kwa acetylcholine (mankhwala ofunikira pophunzira ndi kukumbukira).

Osagwiritsidwa ntchito ngati chithandizo cha matenda a Alzheimer's, huperzine A imanenedwanso kuti imathandizira kuphunzira ndi kukumbukira komanso kuteteza ku kuchepa kwa chidziwitso chokhudzana ndi ukalamba.

Kuonjezera apo, huperzine A nthawi zina amagwiritsidwa ntchito kulimbikitsa mphamvu, kuonjezera tcheru, ndi kuthandizira kuchiza myasthenia gravis (matenda a autoimmune omwe amakhudza minofu).

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| | Chithandizo chamankhwala azitsamba |
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Mankhwala owonjezera a zitsamba amapangidwa ndi zitsamba zomwe zimawononga pang'ono komanso zoyera zomwe zimapangitsa kuvutika kwanu kuzimiririka. Zakudya zowonjezera zitsamba tsopano zikutchuka kwambiri padziko lonse lapansi. Masiku ano, madokotala ambiri amalimbikitsa kuleza mtima kwawo kuti akhale ndi mankhwala azitsamba kuti achire ku matenda amtundu uliwonse omwe ndizosatheka kuchiza mwanjira ina. Mankhwala azitsamba ndi achilengedwe ndipo amagwira ntchito popanda kuwononga thanzi la munthu. Kamodzi mankhwala amakono sanapezeke kuti nthawi yomweyo anthu amakona anayi a dziko lapansi amagwiritsa ntchito mankhwala achilengedwe. Natural mankhwala otchedwa zitsamba. Masiku ano tinkatcha mankhwala azitsamba m'malo mwa zitsamba komanso mankhwala a unani….

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| | Chithandizo chamankhwala azitsamba |

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