[Dzina lachilatini]Huperzia serratum

[Source] Huperziceae therere lonse laku China

[Maonekedwe]Wofiirira mpaka woyera

[Zopangira]Huperzine A

[Matchulidwe]Huperzine A 1% - 5%, HPLC

[Kusungunuka] Kusungunuka mu chloroform, methanol, ethanol, kusungunuka pang'ono m'madzi

[Kukula kwa kachigawo] 80 Mesh

[Kutaya pakuyanika] ≤5.0%

[Chitsulo Cholemera] ≤10PPM

[Zotsalira za mankhwala] EC396-2005, USP 34, EP 8.0, FDA

[Kusungirako] Sungani pamalo ozizira komanso owuma, khalani kutali ndi kuwala kwachindunji ndi kutentha.

[Alumali moyo] 24 Miyezi

[Phukusi] Odzaza ndi mapepala-ng'oma ndi matumba awiri apulasitiki mkati.

[Huperzine A ndi chiyani?

Huperzia ndi mtundu wa moss womwe umamera ku China. Zimagwirizana ndi mosses zamakalabu (banja la Lycopodiaceae) ndipo akatswiri ena amadzimadzi amadziwika kuti Lycopodium serratum. Moss yonse yokonzedwa idagwiritsidwa ntchito mwamwambo. Kukonzekera kwa zitsamba zamakono kumagwiritsa ntchito alkaloid yokhayokha yomwe imadziwika kuti huperzine A. Huperzine A ndi alkaloid yomwe imapezeka mu huperzia yomwe yanenedwa kuti imalepheretsa kuwonongeka kwa acetylcholine, chinthu chofunikira kwambiri chomwe chimafunika ndi dongosolo lamanjenje kuti lipereke chidziwitso kuchokera ku selo kupita ku selo. Kafukufuku wa zinyama wasonyeza kuti mphamvu ya huperzine A yosunga acetylcholine ingakhale yaikulu kuposa ya mankhwala ena olembedwa ndi dokotala. Kutayika kwa ntchito ya acetylcholine ndi gawo loyamba la zovuta zingapo za ubongo, kuphatikizapo matenda a Alzheimer's. Huperzine A itha kukhalanso ndi chitetezo paminyewa yaubongo, ndikuwonjezera kuthekera kwake kothandizira kuchepetsa zizindikiro za zovuta zina zaubongo.

[Ntchito] Yogwiritsidwa ntchito m'mankhwala osagwiritsidwa ntchito masiku onse, huperzine A yapezedwa kuti imakhala ngati cholinesterase inhibitor, mtundu wa mankhwala omwe amagwiritsidwa ntchito poletsa kusweka kwa acetylcholine (mankhwala ofunikira pophunzira ndi kukumbukira).

Osagwiritsidwa ntchito ngati chithandizo cha matenda a Alzheimer's, huperzine A imanenedwanso kuti imathandizira kuphunzira ndi kukumbukira komanso kuteteza ku kuchepa kwa chidziwitso chokhudzana ndi ukalamba.

Kuonjezera apo, huperzine A nthawi zina amagwiritsidwa ntchito kulimbikitsa mphamvu, kuonjezera tcheru, ndi kuthandizira kuchiza myasthenia gravis (matenda a autoimmune omwe amakhudza minofu).

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Kodi Rain Soul ndi chiyani?
Ma Antioxidants Amphamvu a Moyo wa Mvula & Essential Fatty Acids kuti akupatseni nyonga, kutsitsimutsa, kuchotseratu maganizo anu, thupi lanu ndi mzimu wanu. Mbeu yakuda ya chitowe, Mbewu ya rasipiberi yakuda, Mphesa, Ribose-D,Resveratrol.
Wolemera mu antioxidants ndi mafuta acids ofunikira m'thupi la munthu, amathandizira kusokoneza ubongo ndi thupi laumunthu Mabuku akale amalemba kuti mbewu zakuda za chitowe zimatha kugwiritsidwa ntchito ngati mankhwala a matenda aliwonse kupatula kuti sangathe kubweretsanso moyo.

Dr Otto Heinrich Warburg (Germany)
Mphoto ya Nobel mu Medicine 1931: Biochemist
Thupi limafuna mafuta apadera omwe, pakati pa ntchito zina zofunika. zimapangitsa kuti mpweya wokwanira ufike m'maselo kudzera mu nembanemba zama cell. Zomwe zili zofunika, Mafuta apaderawa amayamwa mpweya kwambiri. Otchedwa Essential Fatty Acids, kapena EFAs, mafuta apaderawa ayenera kuperekedwa kuchokera kunja kwa thupi tsiku lililonse.

Black rasipiberi mbewu:
Muli ndi ma phytonutrients ngati antioxidant kuphatikiza ellagitannins ndi anthocyanins. Izi zingathandize kulimbana ndi ma virus, kutupa, ndi zina zingapo zovuta zaumoyo. Antioxidants amafufuza ndikuchotsa zinthu zowononga ma cell, zomwe zimatchedwa ma free radicals. Ma radicals aulere amatha kuchitika mwachilengedwe m'thupi kapena kuchokera pakukhudzidwa ndi poizoni wachilengedwe. Ngakhale kuti ellagitannins amapezeka mu zipatso zambiri, raspberries ndizomwe zimakhala zamphamvu kwambiri.

Black rasipiberi mbewu:
Muli ndi ma phytonutrients ngati antioxidant kuphatikiza ellagitannins ndi anthocyanins. Izi zingathandize kulimbana ndi ma virus, kutupa, ndi zina zingapo zovuta zaumoyo. Antioxidants amafufuza ndikuchotsa zinthu zowononga ma cell, zomwe zimatchedwa ma free radicals. Ma radicals aulere amatha kuchitika mwachilengedwe m'thupi kapena kuchokera pakukhudzidwa ndi poizoni wachilengedwe. Ngakhale kuti ellagitannins amapezeka mu zipatso zambiri, raspberries ndizomwe zimakhala zamphamvu kwambiri.

Mbeu ya mphesa:
Mbeu za mphesa zili ndi gwero lambiri la flavonoids lotchedwa proanthocyanidins. Izi ndizofunikira pa thanzi laubongo chifukwa cha ma free radical-quenching antioxidant ndi zotsatira zoteteza kolajeni.Proanthocyanidins Zawonetsedwanso kuti zimachedwetsa kuyambika kwa lipid peroxidation komanso kuti ma ayoni achitsulo a chelate. Ma ayoni achitsulo aulere ndi ena mwa omwe amalimbikitsa lipid peroxide, hydrogen peroxide ndi hydroxyl radical production. Izi ndizothandizira kwambiri pathogenesis ya matenda a Parkinsons, amodzi mwa matenda omwe amapezeka kwambiri mwa anthu okalamba.

Ribose-D :
Ribose-D ndi shuga wa carbon 5 womwe umapezeka mu selo lililonse la thupi lathu lomwe limaphatikizapo mpweya ndi ATP (adenosine triphoshate) kuti apereke mphamvu ku selo lililonse. Ribose imapezekanso mu RNA (ribonucleic acid), yomwe ndi imodzi mwazinthu zazikulu zonyamula zamoyo. Kupsinjika kwa okosijeni, komwe kumayesedwa ndi kuwonongeka kwakukulu kwa ma cell, kumabweretsa kutupa mwadongosolo. Mwamwayi, matupi athu amatha kuthana ndi vutoli tsiku ndi tsiku. Komabe, ngati matupi athu awona kuwonjezeka kwachilendo kwa ma radicals aulere chifukwa chochita masewera olimbitsa thupi, kupsinjika tsiku ndi tsiku, kusuta kwambiri, kudya mafuta ochulukirapo, chitetezo chamthupi, kukalamba, ndi zina zotero, thupi limakhala lotopa komanso losachita bwino popanga Ribose-D kuti libwezere. mphamvu zama cell. Chifukwa cha izi, tifunika kuwonjezera ndi Ribose-D kuti tikonzenso mphamvu zama cell.
Zotulutsa MphesaResveratrol:
Kutulutsa khungu la mphesa kumakhala ndi trans-resveratrol yomwe imatengedwa kuti ndi mankhwala achilengedwe omwe amatha kulimbana ndi matenda a bakiteriya.Resveratrolzingathandize kuteteza thupi ku matenda osiyanasiyana ndi kuchepetsa ukalamba.

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Nkhani: Biochemistry
Pepala: Metabolism ya ma carbohydrate