[Izina ry'ikilatini] Huperzia serratum

[Source] Huperziceae ibyatsi byose biva mubushinwa

[Kugaragara] Umuhondo kugeza umweru

[Ingredient] Huperzine A.

[Ibisobanuro] Huperzine A 1% - 5%, HPLC

[Solubility] Gushonga muri chloroform, methanol, Ethanol, gushonga gato mumazi

[Ingano ya Particle] 80 Mesh

[Gutakaza kumisha] ≤5.0%

[Icyuma Cyinshi] ≤10PPM

[Ibisigisigi byica udukoko] EC396-2005, USP 34, EP 8.0, FDA

[Ububiko] Bika ahantu hakonje & humye, irinde urumuri rwinshi nubushyuhe.

[Ubuzima bwa Shelf] Amezi 24

[Gupakira] Bipakiye mu mpapuro-ingoma no mu mifuka ibiri ya pulasitike imbere.

[Huperzine A]

Huperzia ni ubwoko bwa moss ikura mubushinwa. Ifitanye isano na mose ya club (umuryango wa Lycopodiaceae) kandi izwi nabamwe mubimera nka Lycopodium serratum. Mose yateguwe yose yakoreshejwe gakondo. Imiti y'ibyatsi igezweho ikoresha gusa alkaloide yitaruye izwi ku izina rya huperzine A. Huperzine A ni alkaloide iboneka muri huperzia yavuzwe ko irinda isenyuka rya acetyloline, ikintu cy'ingenzi gikenerwa na sisitemu y'imitsi kugira ngo ikwirakwize amakuru ava mu ngirabuzimafatizo. Ubushakashatsi bw’inyamaswa bwagaragaje ko ubushobozi bwa huperzine A bwo kubika acetyloline bushobora kuba bwinshi kuruta ubw'imiti imwe n'imwe yandikiwe. Gutakaza imikorere ya acetylcholine nikintu cyibanze kiranga ibibazo byinshi byimikorere yubwonko, harimo n'indwara ya Alzheimer. Huperzine A irashobora kandi kugira ingaruka zo kurinda ingirangingo zubwonko, bikarushaho kongera ubushobozi bwayo bwo gufasha kugabanya ibimenyetso byindwara zimwe na zimwe zubwonko.

[Imikorere] Yifashishijwe mu buvuzi butandukanye, huperzine A yasanze ikora nka inhibitori ya cholinesterase, ubwoko bwimiti ikoreshwa mu gukumira isenyuka rya acetyloline (imiti ikenewe mu kwiga no kwibuka).

Ntabwo ikoreshwa gusa mu kuvura indwara ya Alzheimer, huperzine A ivugwa kandi ko izamura imyigire no kwibuka ndetse no kwirinda kugabanuka kw’imyaka.

Byongeye kandi, huperzine A rimwe na rimwe ikoreshwa mu kongera ingufu, kongera ubukangurambaga, no gufasha mu kuvura indwara ya myasthenia gravis (indwara ya autoimmune ifata imitsi).

Drew Kelley