[Izina ry'ikilatini] Huperzia serratum

[Source] Huperziceae ibyatsi byose biva mubushinwa

[Kugaragara] Umuhondo kugeza umweru

[Ingredient] Huperzine A.

[Ibisobanuro] Huperzine A 1% - 5%, HPLC

[Solubility] Gushonga muri chloroform, methanol, Ethanol, gushonga gato mumazi

[Ingano ya Particle] 80 Mesh

[Gutakaza kumisha] ≤5.0%

[Icyuma Cyinshi] ≤10PPM

[Ibisigisigi byica udukoko] EC396-2005, USP 34, EP 8.0, FDA

[Ububiko] Bika ahantu hakonje & humye, irinde urumuri rwinshi nubushyuhe.

[Ubuzima bwa Shelf] Amezi 24

[Gupakira] Bipakiye mu mpapuro-ingoma no mu mifuka ibiri ya pulasitike imbere.

[Huperzine A]

Huperzia ni ubwoko bwa moss ikura mubushinwa. Ifitanye isano na mose ya club (umuryango wa Lycopodiaceae) kandi izwi nabamwe mubimera nka Lycopodium serratum. Mose yateguwe yose yakoreshejwe gakondo. Imiti y'ibyatsi igezweho ikoresha gusa alkaloide yitaruye izwi ku izina rya huperzine A. Huperzine A ni alkaloide iboneka muri huperzia yavuzwe ko irinda isenyuka rya acetyloline, ikintu cy'ingenzi gikenerwa na sisitemu y'imitsi kugira ngo ikwirakwize amakuru ava mu ngirabuzimafatizo. Ubushakashatsi bw’inyamaswa bwerekanye ko ubushobozi bwa huperzine A bwo kubika acetyloline bushobora kuba bwinshi kuruta ubw'imiti imwe n'imwe yandikiwe. Gutakaza imikorere ya acetylcholine nikintu cyibanze kiranga ibibazo byinshi byimikorere yubwonko, harimo n'indwara ya Alzheimer. Huperzine A irashobora kandi kugira ingaruka zo kurinda ingirangingo zubwonko, bikarushaho kongera ubushobozi bwayo bwo gufasha kugabanya ibimenyetso byindwara zimwe na zimwe zubwonko.

[Imikorere] Yifashishijwe mu buvuzi butandukanye, huperzine A yasanze ikora nka inhibitori ya cholinesterase, ubwoko bwimiti ikoreshwa mu gukumira isenyuka rya acetyloline (imiti ikenewe mu kwiga no kwibuka).

Ntabwo ikoreshwa gusa mu kuvura indwara ya Alzheimer, huperzine A ivugwa kandi ko izamura imyigire no kwibuka ndetse no kwirinda kugabanuka kw’imyaka.

Byongeye kandi, huperzine A rimwe na rimwe ikoreshwa mu kongera ingufu, kongera ubukangurambaga, no gufasha mu kuvura indwara ya myasthenia gravis (indwara ya autoimmune ifata imitsi).

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Muraho basore, uyumunsi nateguye videwo kubyerekeranye no gukuramo byoroshye cyane nukuvuga krahisi yo guteka ibirayi hamwe nikizamini cyacyo ugereranije na tincure yubucuruzi bwa iyode. Mbere yo gutangira amagambo abiri gusa yerekeye krahisi. ni polymer karemano iboneka mumuceri, ceral, ibirayi kandi ni isoko yingufu kubinyabuzima.
Igizwe na polymers ebyiri zitandukanye: amylose 20% na amilopecten 80%. Byombi ni iminyururu igizwe nubumwe bwa alpha glucose. Hano turashobora kubona ishusho yoroshye ya molekile ya krahisi igoye cyane.
Reka dutangire. Inzira iroroshye kuburyo umwana ashobora kubikora nta kibazo. Fata gusa garama ijana ibirayi hanyuma ubishishure. Noneho byoroshye. Bimaze gukorwa shyira kuri beaker hamwe na milimetero magana abiri y'amazi ashyushye. Noneho vanga muminota imwe-ibiri. Noneho uyungurure hamwe nuwatetse akayunguruzo kubindi bikoresho. Hamwe nigice kirambye nukuvuga ibirayi byasizwe urashobora gusubiramo ibikorwa inshuro nyinshi wongeyeho amazi ukavanga, ukongera ukayungurura ariko ibi birashoboka. Nyuma yiminota 5-10 ya krahisi, kudashonga mumazi bizagwa. Hano turashobora kubona imvura yera, yera yuzuye. Kwimura gusa icyiciro cyamazi kurindi beaker uzatandukanya ibicuruzwa. Reka byume mubushyuhe bwicyumba. Hano turashobora kubona ibinyamisogwe kandi bigaragara ko byera, amavuta make ariko nyuma ya essiccation bizaba cristalline.
Noneho, kugirango tumenye ko ari ibinyamisogwe ntabwo ari ifu yubumaji, tuzakoresha tincure ya iyode (ivanze na Ethanol, amazi, potasiyumu iyode na iyode yibanze). Kugirango ugerageze shyira ibinyamisogwe mumiyoboro yipimisha hamwe namazi hanyuma uranyeganyega. Nyuma yo kongeramo tincure ya iyode ushobora kuvanga namazi cyangwa ntayo. Ariko, igisubizo kizahinduka ibara ry'ubururu bwijimye. Ikibaho nuko ioni iyode (I3-) ikomatanya na amilose kandi bigatuma ibice bifata ibara.
Ndabaramukije, tuzakubona kubigeragezo bitaha.