[Lebitso la Selatine]Huperzia serratum

[Mohloli] Huperziceae setlama se tsoang Chaena

[Ponahalo]Sootho ho isa bosoeu

[Motsoako]Huperzine A

[Tlhaloso]Huperzine A 1% - 5%, HPLC

[Solubility] E qhibiliha ka chloroform, methanol, ethanol, e qhibiliha hanyenyane metsing.

[Karolo ea boholo] 80 Mesh

[Tahlehelo ha o omisoa] ≤5.0%

[Heavy Metal] ≤10PPM

[Masala a chefo e bolaeang likokoanyana] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Boloka sebakeng se pholileng le se omileng, qoba ho khanya le mocheso.

[Shelofo bophelo] 24 Likhoeli

[Package] E pakiloe ka meropa ea pampiri le mekotla e 'meli ea polasetiki ka hare.

[Huperzine A ke eng]

Huperzia ke mofuta oa boriba bo melang Chaena. E amana le mosi oa lihlopha (lelapa la Lycopodiaceae) 'me litsebi tse ling tsa limela li tsejoa e le Lycopodium serratum. Boriba bohle bo lokisitsoeng bo ne bo sebelisoa ka moetlo. Litokisetso tsa kajeno tsa litlama li sebelisa feela alkaloid e ka thōko e tsejoang e le huperzine A. Huperzine A ke alkaloid e fumanoang huperzia e tlalehiloeng ho thibela ho senyeha ha acetylcholine, ntho ea bohlokoa e hlokoang ke tsamaiso ea methapo ho fetisetsa boitsebiso ho tloha seleng ho ea ho sele. Lipatlisiso tsa liphoofolo li bontšitse hore bokhoni ba huperzine A ba ho boloka acetylcholine bo ka ba boholo ho feta ba lithethefatsi tse ling tsa ngaka. Ho lahleheloa ke mosebetsi oa acetylcholine ke tšobotsi e ka sehloohong ea mathata a mangata a boko, ho akarelletsa lefu la Alzheimer's. Huperzine A e ka boela ea ba le phello e sireletsang liseleng tsa boko, ea eketsa bokhoni ba eona ba ho thusa ho fokotsa matšoao a mathata a mang a boko.

[Mosebetsi] Ha e sebelisoa mekhoeng e meng ea phekolo, ho fumanoe hore huperzine A e sebetsa e le cholinesterase inhibitor, mofuta oa moriana o sebelisetsoang ho thibela ho senyeha ha acetylcholine (k’hemik’hale e hlokahalang bakeng sa ho ithuta le ho hopola).

Ha e sebelisoe feela e le phekolo ea lefu la Alzheimer, huperzine A e boetse e boleloa hore e matlafatsa ho ithuta le mohopolo le ho sireletsa khahlanong le ho fokotseha ha kelello ho amanang le lilemo.

Ho phaella moo, ka linako tse ling huperzine A e sebelisetsoa ho matlafatsa matla, ho eketsa ho falimeha, le ho thusa ho phekola myasthenia gravis (lefu la autoimmune le amang mesifa).

Mokuli enoa o ile a etsoa "microsurgical resection" ea glioblastoma multiforme e atolositsoeng. Hemostasis e felletseng e fihletsoe ka metsotsoana e 332 ka ts'ebeliso ea MPH. Ha ho na hemostat e eketsehileng ea topical kapa coagulation ea motlakase e sebelisitsoeng bakeng sa ho koala hemostasis. CT-imaging ea postoperative cranial ha e senole ho tsoa mali
pherekano.

Lintlha tsena li nkiloe ho Safety and Efficacy of MicroporousPolysaccharide Hemospheres in Neurosurgery, buka e ngotsoeng ka letsoho e ka baloang mona https://journals.lww.com/neurosurgery/Fulltext/2011/09007/Safety_and_Efficacy_of_Microporous_Polysaccharide.8.aspx. E rometsoe ke sengoli se ngollanang Joachim Oertel, MD, ho tsoa ho Neurochirurgische Klinik e Mainz, Jeremane.

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