[Igama lesiLatini] Vitis vinifera Linn

[Umthombo weZityalo] Imbewu yomdiliya evela eYurophu

[Iinkcukacha] 95%OPCs;45-90% polyphenols

[Imbonakalo] Umgubo obomvu omdaka

[Inxalenye yesityalo esetyenzisiweyo]: imbewu

[Ubungakanani besuntswana] 80 Mesh

[Ilahleko ekomisweni] ≤5.0%

[Intsimbi enzima] ≤10PPM

[Intsalela yesitshabalalisi] EC396-2005, USP 34, EP 8.0, FDA

[Ugcino] Gcina kwindawo epholileyo neyomileyo, gcina kude nokukhanya okuthe ngqo kunye nobushushu.

[Ubomi beShelufu] Iinyanga ezingama-24

[Ipakethi] Ipakishwe ngamadubhu ephepha kunye neengxowa ezimbini zeplastiki ngaphakathi.

[Uphawu jikelele]

1. Imveliso yethu iphumelele uvavanyo lwe-ID nguChromaDex, i-Alkemist Lab. kunye nezinye

amaziko ovavanyo agunyazisiweyo wesithathu, afana nokubhaqwa;

2. Iintsalela ze-pesticide zihambelana (EC) No 396/2005 USP34, EP8.0, FDA kunye neminye imigangatho kunye nemimiselo ye-pharmacopoeia yangaphandle;

3. Isinyithi esinzima ngokuhambelana ngokuthe ngqo nolawulo oluqhelekileyo lwe-pharmacopoeia yangaphandle, njenge-USP34, EP8.0, FDA, njl.;

4. Inkampani yethu imise isebe kwaye ingenise izinto eziluhlaza ngokuthe ngqo ukusuka eYurophu kunye nolawulo olungqongqo lwentsimbi enzima kunye nentsalela ye-pesticide. I-Aslo iqinisekisa ukuba umxholo weprocyanidins kwimbewu yomdiliya ungaphezulu kwe-8.0%.

5. Ii-OPCs ngaphezu kwe-95%, i-polyphenol ngaphezu kwe-70%, umsebenzi ophezulu, ukuchasana kwe-oxidation kunamandla, i-ORAC ngaphezu kwe-11000.

[Umsebenzi]

Iidiliya (Vitis vinifera) ziye zaziswa ngexabiso lamayeza kunye nesondlo kumawaka eminyaka. AmaJiphutha ayesitya iidiliya kudala kakhulu, kwaye uninzi lweentanda-bulumko zamandulo zamaGrike zathetha ngamandla okuphilisa ediliya - ngokuqhelekileyo ikwimo yewayini. Amaxhwele aseYurophu enza i-ointment kwincindi yomdiliya ukunyanga izifo zesikhumba kunye namehlo. Amagqabi omdiliya ayesetyenziselwa ukunqanda ukopha, ukudumba, neentlungu, ezinjengohlobo oluziswa yihemorrhoids. Imidiliya engekavuthwa yayisetyenziselwa ukunyanga umqala obuhlungu, kwaye iidiliya ezomisiweyo (iirasentyisi) zazisetyenziselwa ukuqunjelwa kunye nonxano. Iidiliya ezijikelezayo, ezivuthiweyo, eziswiti zazisetyenziselwa ukunyanga uluhlu lweengxaki zempilo ezibandakanya umhlaza, ikholera, ingqakaqha, isicaphucaphu, usulelo lwamehlo, nolusu, izintso, kunye nezifo zesibindi.

Izicatshulwa zembewu yomdiliya ziphuma kwimizi-mveliso ephuma kwimbewu yomdiliya epheleleyo enevithamin E, i-flavonoids, i-linoleic acid kunye ne-phenolic OPCs. Ithuba lokuthengisa eliqhelekileyo lokukhupha izinto zembewu yomdiliya leleekhemikhali ezaziwa ngokuba ziipolyphenols ezine-antioxidant function in vitro.

Isishwankathelo sevidiyo sephepha loPhando loQoqosho "I-Ulva lactuca polysaccharides ikhusela i-Wistar rat breast carcinogenesis ngokwandisa i-apoptosis, ukuphuculwa kwenkqubo yokukhusela i-antioxidant, kunye nokunyanzeliswa kokuvuvukala" epapashwe kwijenali yokufikelela evulekileyo kwi-Breast Cancer-Iithagethi kunye noNyango ngu-Abd-Ellatef et al. .

Imvelaphi: Kutshanje, izifundo zophando ezininzi ziye zajolisa ekwahluleni nasekusebenzeni kweepolysaccharides eziphuma kwiintlobo ezahlukeneyo ze-algal, eziveze imisebenzi emininzi yebhayoloji efana ne-antioxidant kunye ne-antitumor. Olu phononongo luvavanya iipropathi ezinokubakho zomhlaza webele we-chemopreventive zokhula lwaselwandle oluqhelekileyo, i-lettuce yolwandle, i-Ulva lactuca (ulvan) i-polysaccharides isebenzisa i-in vitro bioassays kumgca weseli yomhlaza webele womntu (MCF-7) kunye nemodeli yezilwanyana ye-vivo ye-breast carcinogenesis.
Iindlela: Impembelelo ye-Cytotoxic ye-ulvan polysaccharides kwi-MCF-7 yavavanywa kwi-vitro. Kuphando lwe-vivo, idosi enye ye-25 mg / kg ubunzima bomzimba 7,12-dimethylbenz[a]anthracene (DMBA) kunye ne-ulvan polysaccharides (50 mg / kg ubunzima bomzimba yonke imihla) kwiiveki ze-10 zalawulwa ngomlomo Iimpuku zeWistar.
Iziphumo: Ukuguqulwa kwe-histopathological ye-Deleterious kwizicubu zesifuba ezibandakanya i-papillary cyst adenoma kunye ne-hyperplasia ye-ductal epithelial lining kunye ne-intraluminal necrotic materials kunye nokubala kwabonwa kwiqela elilawulwa yi-DMBA. Ezi zilonda ziye zathintelwa kwiqela elilawulwa yi-DMBA eliphathwa nge-ulvan polysaccharides. Amacandelo e-immunohistochemical abonisa ukuba unyango lweegundane ezilawulwa yi-DMBA kunye ne-ulvan polysaccharides zonyuse ngokuphawulekayo iprotheni ye-pro-apoptotic ethotyiweyo, i-p53, kwaye yehla i-anti-apoptotic ephakamileyo.
umakisha, bcl2, ukubonakaliswa kwithishu yebele. Ukuphakama kwe-lipid peroxidation kunye nemisebenzi ecinezelweyo ye-antioxidant ye-enzyme kulawulo olulawulwa yi-DMBA ithintelwe kakhulu.
unyango nge-ulvan polysaccharides. Amanqanaba aphakanyisiweyo e-cytokines tumor necrosis factor-α kunye ne-nitric oxide aye aphuculwa kakhulu kwiimpuku ezilawulwa yi-DMBA eziphathwa nge-ulvan polysaccharides xa kuthelekiswa nolawulo olulawulwa yi-DMBA.
Isiphelo: Ukuqukumbela, i-ulvan polysaccharides kwinqanaba lokuqalisa kunye nokukhuthazwa kunokuba nemiphumo enokubakho ye-chemopreventive ngokuchasene ne-breast carcinogenesis. Ezi ziphumo zokuthintela
inokuba ngumlamli ngokwandiswa kwe-apoptosis, ukunyanzeliswa koxinzelelo lwe-oxidative kunye nokuvuvukala, kunye nokwandiswa kwenkqubo yokukhusela i-antioxidant.

Funda iphepha lokuqala loPhando apha https://doi.org/10.2147/BCTT.S125165

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