[Igama lesiLatini]Huperzia serratum

[Umthombo] Huperziceae yonke imifuno evela eTshayina

[Imbonakalo] Brown ukuya mhlophe

[Isithako]Huperzine A

[Ingcaciso]Huperzine A 1% – 5%, HPLC

[Ukunyibilika] Inyibilika kwichloroform, methanol, ethanol, inyibilika kancinane emanzini.

[Ubungakanani besuntswana] 80 Mesh

[Ilahleko ekomisweni] ≤5.0%

[Intsimbi enzima] ≤10PPM

[Intsalela yesitshabalalisi] EC396-2005, USP 34, EP 8.0, FDA

[Ugcino] Gcina kwindawo epholileyo neyomileyo, gcina kude nokukhanya okuthe ngqo kunye nobushushu.

[Ubomi beShelufu] Iinyanga ezingama-24

[Ipakethi] Ipakishwe ngamadubhu ephepha kunye neengxowa ezimbini zeplastiki ngaphakathi.

[Yintoni iHuperzine A]

IHuperzia luhlobo lobulembu obukhula eTshayina. Inxulumene nobulembu beklabhu (usapho lweLycopodiaceae) kwaye yaziwa kwezinye iingcali ngezityalo njengeLycopodium serratum. I-moss yonke elungisiweyo yayisetyenziswe ngokwesiko. Amalungiselelo amayeza anamhlanje asebenzisa kuphela i-alkaloid ekwanti eyaziwa ngokuba yi-huperzine A. I-Huperzine A yi-alkaloid efumaneka kwi-huperzia eye yaxelwa ukunqanda ukuchithwa kwe-acetylcholine, into ebalulekileyo efunekayo yinkqubo ye-nervous yokuhambisa ulwazi kwiseli ukuya kwiseli. Uphando lwezilwanyana lucebise ukuba amandla e-huperzine A okugcina i-acetylcholine inokuba nkulu kuneyamanye amayeza kagqirha. Ukulahlekelwa ngumsebenzi we-acetylcholine luphawu oluphambili lweengxaki ezininzi zokusebenza kwengqondo, kuquka nesifo se-Alzheimer. I-Huperzine A inokuba nefuthe elikhuselayo kwizicubu zobuchopho, inyuse ngakumbi amandla ayo okucinga ukunceda ukunciphisa iimpawu zokuphazamiseka kwengqondo.

[Umsebenzi] Isetyenziswe kunyango olulolunye, i-huperzine A ifunyenwe isebenza njenge-cholinesterase inhibitor, uhlobo lweyeza elisetyenziselwa ukuthintela ukuchithwa kwe-acetylcholine (ikhemikhali ebalulekileyo yokufunda kunye nememori).

Ayisetyenziswanga kuphela njengonyango lwe-Alzheimer's, i-huperzine A ikwatsho ukuba iphucule ukufunda kunye nenkumbulo kunye nokukhusela ekunciphiseni kwengqondo okunxulumene neminyaka.

Ukongezelela, i-huperzine A ngamanye amaxesha isetyenziselwa ukunyusa amandla, ukwandisa ukuphaphama, kunye nokunceda unyango lwe-myasthenia gravis (i-autoimmune disorder echaphazela imisipha).

Drew Kelley