[Igama lesiLatini]I-Hypericum perforatum

[Umthombo weZityalo] Ovela eTshayina

[Imbonakalo] Umgubo ocolekileyo omdaka

[Iinkcukacha] 0.3% Hypericin

[Ubungakanani besuntswana] 80 Mesh

[Ilahleko ekomisweni] ≤5.0%

[Intsimbi enzima] ≤10PPM

[Intsalela yesitshabalalisi] EC396-2005, USP 34, EP 8.0, FDA

[Ugcino] Gcina kwindawo epholileyo neyomileyo, gcina kude nokukhanya okuthe ngqo kunye nobushushu.

[Ipakethi] Ipakishwe ngamadubhu ephepha kunye neengxowa ezimbini zeplastiki ngaphakathi.

[Yintoni i-St. John's wort]

John's wort (Hypericum perforatum) inembali yokusetyenziswa njengeyeza elibuyela kwiGrisi yamandulo, apho yayisetyenziselwa izifo ezininzi, kuquka ukuphazamiseka kwemizwa eyahlukeneyo. I-St. John's wort nayo ine-antibacterial, antioxidant, kunye ne-antiviral properties. Ngenxa yezinto zayo ezichasayo, isetyenziswe esikhumbeni ukunceda ukuphilisa amanxeba kunye nokutshisa. John's wort yenye yezona mveliso zamayeza ezithengwa ngokuqhelekileyo eUnited States.

Kwiminyaka yakutshanje, iSt. John’s wort iye yaphononongwa ngokubanzi njengonyango lodandatheko. Uphononongo oluninzi lubonisa ukuba i-St. John's wort inokunceda ukunyanga ukudakumba okuphakathi ukuya kophakathi, kwaye ineziphumo ebezingalindelekanga ezimbalwa kunezinye ii-antidepressants ezichazwe ngugqirha.

[Imisebenzi]

1. Iimpawu ezichasayo kunye nezokuthomalalisa;

2. Isilungiso esisebenzayo kwisistim se-nervous, i-tension ephumlayo, kunye nexhala kunye nokunyusa imimoya;

3. Ukuchasana nokudumba

4. Ukuphucula ukujikeleza kwe-capillary

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I-Milk Thistle (i-Silybum marianum) yimifuno yaseYurophu, engaphezulu kweminyaka engama-2000 yokusetyenziswa komntu, esetyenziselwa isifo sesibindi, kodwa ngaba isebenza ngokwenene? Fumana apha!

Uncwadi lweNzululwazi:

Bosch-Barrera, J., & Menendez, JA (2015). I-Silibinin kunye ne-STAT3: Indlela yendalo yokujolisa kwizinto ezibhaliweyo kunyango lomhlaza. Uphononongo loNyango lweCancer, 41 (6), 540-546. - https://www.ncbi.nlm.nih.gov/pubmed/25944486

Bosch-Barrera, J., Sais, E., Cañete, N., Morocco, J., Cuyàs, E., Izquierdo, A., … Menendez, JA (2016). Impendulo ye-metastasis yobuchopho ukusuka kwizigulane zomhlaza wemiphunga ukuya kwimveliso yomlomo ye-nutraceutical ene-silibinin. Oncotarget, 7(22), 32006-32014. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077992/pdf/oncotarget-07-32006.pdf

Freedman, ND, Curto, TM, Morishima, C., Seeff, LB, Goodman, ZD, Wright, EC, … IQela lovavanyo lwe-HALT-C. (2011).Silymarin ukusetyenziswa kunye nokuqhubela phambili kwesifo sesibindi kulingo lwe-HALT-C. I-Alimentary Pharmacology & Therapeutics, 33 (1), 127-137. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490214/pdf/nihms415758.pdf

Freitag, AF, Cardia, GFE, da Rocha, BA, Aguiar, RP, Silva-Comar, FM de S., Spironello, RA, … Cuman, RKN (2015). I-Hepatoprotective effect ye-silymarin (i-Silybum marianum) kwi-hepatotoxicity eyenziwa yi-acetaminophen kwiigundane ezizenzekelayo. Ubungqina obuSekwe kwiNgxaki eyongezelelweyo kunye neyeza elilolunye : eCAM, 2015, 538317. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363982/pdf/ECAM2015-538317.pdf

Hong, M., Li, S., Tan, HY, Wang, N., Tsao, S.-W., & Feng, Y. (2015). Ubume bangoku bamayeza e-herbal kunyango lwesifo sesibindi esingapheliyo: Iziphumo zebhayoloji, iithagethi zemolekyuli kunye nethemba elizayo. Ijenali yeHlabathi yeeSayensi zeMolekyuli, i-16 (12), i-28705-28745. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691073/pdf/ijms-16-26126.pdf

Kawaguchi-Suzuki, M., Frye, RF, Zhu, H.-J., Brinda, BJ, Chavin, KD, Bernstein, HJ, & Markowitz, JS (2014). Iziphumo zobisi thistle (Silybum marianum) kwi-cytochrome yabantu P450 umsebenzi. I-Metabolism yeziyobisi kunye neSimo, i-42 (10), i-1611-1616. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164972/pdf/dmd.114.057232.pdf

Kumar, R., Deep, G., & Agarwal, R. (2015). Isishwankathelo somhlaza wolusu we-ultraviolet B ngemitha ye-chemoprevention nge-silibinin. IiNgxelo zangoku ze-Pharmacology, 1(3), 206-215. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471873/pdf/nihms-672250.pdf

Lazzeroni, M., Guerrieri-Gonzaga, A., Gandini, S., Johansson, H., Serrano, D., Cazzaniga, M., ... & Bonanni, B. (2016). Uphononongo lwangaphambi kokuhlinzwa lwe-silybin-phosphatidylcholine yomlomo kwizigulana ezinomhlaza webele wokuqala. UPhando loThintelo lweCancer, 9 (1), 89-95. - https://cancerpreventionresearch.aacrjournals.org/content/canprevres/9/1/89.full.pdf

Schrieber, SJ, Hawke, RL, Wen, Z., Smith, PC, Reddy, KR, Wahed, AS, … Fried, MW (2011). Ukwahluka kwi-disposition ye-silymarin phakathi kwezigulane ezine-non-alcoholic fatty disease kunye ne-hepatitis C engapheliyo. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226378/pdf/zdd2182.pdf

Surai, PF (2015).Silymarin njenge-antioxidant yendalo: Isishwankathelo sobungqina obukhoyo kunye nemibono. I-Antioxidants, i-4 (1), i-204-247. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665566/
Yang, Z., Zhuang, L., Lu, Y., Xu, Q., & Chen, X. (2014). Iziphumo kunye nokunyamezela kwe-silymarin (i-milk thistle) kwizigulane ezingapheliyo zentsholongwane ye-hepatitis C: i-meta-analysis yezilingo ezilawulwa ngokungahleliwe. I-BioMed Research International, 2014, 941085. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163440/pdf/BMRI2014-941085.pdf

Wu, J.-P., Tsai, C.-C., Yeh, Y.-L., Lin, Y.-M., Lin, C.-C., Day, CH, … Huang, C.- Y. (2015).Silymarin ikhawulezisa ukuvuselelwa kwesibindi emva kwe-hepatectomy engaphelelanga. Ubungqina obuSekwe kwiNgxaki eyongezelelweyo kunye neyeza elilolunye : eCAM, 2015, 603529. - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539063/pdf/ECAM2015-603529.pdf

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