[Igama lesiLatini]Huperzia serratum

[Umthombo] Huperziceae yonke imifuno evela eTshayina

[Imbonakalo] Brown ukuya mhlophe

[Isithako]Huperzine A

[Ingcaciso]Huperzine A 1% – 5%, HPLC

[Ukunyibilika] Inyibilika kwichloroform, methanol, ethanol, inyibilika kancinane emanzini.

[Ubungakanani besuntswana] 80 Mesh

[Ilahleko ekomisweni] ≤5.0%

[Intsimbi enzima] ≤10PPM

[Intsalela yesitshabalalisi] EC396-2005, USP 34, EP 8.0, FDA

[Ugcino] Gcina kwindawo epholileyo neyomileyo, gcina kude nokukhanya okuthe ngqo kunye nobushushu.

[Ubomi beShelufu] Iinyanga ezingama-24

[Ipakethi] Ipakishwe ngamadubhu ephepha kunye neengxowa ezimbini zeplastiki ngaphakathi.

[Yintoni iHuperzine A]

IHuperzia luhlobo lobulembu obukhula eTshayina. Inxulumene nobulembu beklabhu (usapho lweLycopodiaceae) kwaye yaziwa kwezinye iingcali ngezityalo njengeLycopodium serratum. I-moss yonke elungisiweyo yayisetyenziswe ngokwesiko. Amalungiselelo amayeza anamhlanje asebenzisa kuphela i-alkaloid ekwanti eyaziwa ngokuba yi-huperzine A. I-Huperzine A yi-alkaloid efumaneka kwi-huperzia eye yaxelwa ukunqanda ukuchithwa kwe-acetylcholine, into ebalulekileyo efunekayo yinkqubo ye-nervous yokuhambisa ulwazi kwiseli ukuya kwiseli. Uphando lwezilwanyana lucebise ukuba amandla e-huperzine A okugcina i-acetylcholine inokuba nkulu kuneyamanye amayeza kagqirha. Ukulahlekelwa ngumsebenzi we-acetylcholine luphawu oluphambili lweengxaki ezininzi zokusebenza kwengqondo, kuquka nesifo se-Alzheimer. I-Huperzine A inokuba nefuthe elikhuselayo kwizicubu zobuchopho, inyuse ngakumbi amandla ayo okucinga ukunceda ukunciphisa iimpawu zokuphazamiseka kwengqondo.

[Umsebenzi] Isetyenziswe kunyango olulolunye, i-huperzine A ifunyenwe isebenza njenge-cholinesterase inhibitor, uhlobo lweyeza elisetyenziselwa ukuthintela ukuchithwa kwe-acetylcholine (ikhemikhali ebalulekileyo yokufunda kunye nememori).

Ayisetyenziswanga kuphela njengonyango lwe-Alzheimer's, i-huperzine A ikwatsho ukuba iphucule ukufunda kunye nenkumbulo kunye nokukhusela ekunciphiseni kwengqondo okunxulumene neminyaka.

Ukongezelela, i-huperzine A ngamanye amaxesha isetyenziselwa ukunyusa amandla, ukwandisa ukuphaphama, kunye nokunceda unyango lwe-myasthenia gravis (i-autoimmune disorder echaphazela imisipha).

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Molweni bafana, namhlanje ndilungiselele ividiyo malunga nokutsalwa okulula kakhulu oko kukuthi isitashi ekuphekeni amazambane kunye novavanyo oluhambelanayo kunye ne-tincture yorhwebo ye-iodine. Phambi kokuba uqale amagama amabini nje malunga nesitatshi. yipolymer yendalo ekhoyo kwirayisi, i-ceral, iitapile kwaye ngumthombo wamandla kwizidalwa eziphilayo.
Iqulunqwe ngeepholima ezimbini ezahlukeneyo: i-amylose 20% kunye ne-amilopecten 80%. Omabini ngamatyathanga aqulunqwe ziiyunithi ze-alpha glucose. Apha sinokubona umfanekiso owenziwe lula wemolekyuli yesitatshi entsokothe ​​ngakumbi.
Ngoku masiqalise. Inkqubo ilula kangangokuba nomntwana angayenza loo nto ngaphandle kweengxaki. Thatha nje ikhulu leegram zetapile kwaye uyixobe. Ngoku yigrate ngokulula. Xa sele igqityiwe yibeke kwibeaker enamakhulu amabini eemilimitha zamanzi ashushu. Ngoku xuba malunga nemizuzu enye-mibini. Emva koko hluza ngesihluzo sokupheka kwesinye isikhongozeli. Ngenxalenye ehlala ihleli oko kukuthi iitapile egayiweyo ungaphinda usebenze amaxesha amaninzi ukongeza amanzi kunye nokuxuba, kunye nokuhluza kwakhona kodwa oku kukhetho. Emva kwemizuzu emi-5-10 yesitatshi, enganyibilikiyo emanzini iya kuphuma. Apha sinokubona imvula emhlophe, isitatshi esisulungekileyo. Ukuhambisa nje inqanaba lolwelo kwenye ibhekile uya kwahlula imveliso. Yiyeke yome kwiqondo lokushisa. Apha sinokubona isitashi kwaye sibonakala simhlophe, sincinci kancinci kodwa emva kwe-esiccation iya kuba yikristalline.
Ngoku, ukuvavanya ukuba sistatshi ngenene hayi umgubo womlingo, siya kusebenzisa i-tincture ye-iodine (umxube we-ethanol, amanzi, i-iodide ye-potassium kunye ne-elemental iodine). Ukuyivavanya faka istatshi kwityhubhu yovavanyo enamanzi kwaye ungcangcazele. Emva kokongeza i-tincture ye-iodine onokuyihlambulula ngamanzi okanye hayi. Nangona kunjalo, isisombululo siya kuba nombala oluhlaza okwesibhakabhaka. Yintoni eyenzekayo kukuba i-iodine ions (I3- ) idibanisa kwi-amilose kwaye yenza i-compound ithathe lo mbala.
Imibuliso yam, sibonane kuvavanyo olulandelayo.