[Igama lesiLatini] Sophora Japonica L

[Umthombo Wezitshalo] waseShayina

[Imininingwane] 90%-99%

[Ukubonakala] Impushana eyikristalu ephuzi

Ingxenye Yesitshalo Esetshenzisiwe:I-Bud

[Usayizi wezinhlayiyana] 80 Mesh

[Ukulahlekelwa lapho omiswa] ≤12.0%

[Insimbi Esindayo] ≤10PPM

[Isitoreji] Gcina endaweni epholile neyomile, gwema ukukhanya nokushisa okuqondile.

[Impilo yeshelufu] Izinyanga ezingama-24

[Iphakheji] Ipakishwe ngezigubhu zephepha kanye nezikhwama zepulasitiki ezimbili ngaphakathi.

[Isisindo esiphelele] 25kgs/isigubhu

Isingeniso esifushane

I-Quercetin i-pigment yesitshalo (i-flavonoid). Itholakala ezitshalweni eziningi nokudla, njengewayini elibomvu, u-anyanisi, itiye eliluhlaza, ama-apula, amajikijolo, i-Ginkgo biloba, i-St. John's wort, umdala waseMelika, nabanye. Itiye le-Buckwheat linenani elikhulu le-quercetin. Abantu basebenzisa i-quercetin njengomuthi.

I-Quercetin isetshenziselwa ukwelapha izimo zenhliziyo nemithambo yegazi kuhlanganise “nokuqina kwemithambo yegazi” (i-atherosclerosis), i-cholesterol ephezulu, isifo senhliziyo, nezinkinga zokujikeleza kwegazi. Ibuye isetshenziselwe isifo sikashukela, ulwelwesi lwama-cataract, i-hay fever, i-peptic ulcer, i-schizophrenia, ukuvuvukala, isifuba somoya, i-gout, izifo ezibangelwa amagciwane, i-chronic fatigue syndrome (CFS), ukuvimbela umdlavuza, kanye nokwelapha izifo ezingelapheki ze-prostate. I-Quercetin nayo isetshenziselwa ukwandisa ukukhuthazela nokuthuthukisa ukusebenza kwezemidlalo.

Umsebenzi Oyinhloko

I-1.I-Quercetin ingase ikhiphe i-phlegm futhi ibambe ukukhwehlela, ingasetshenziswa futhi njenge-anti-asthmatic.

2. I-Quercetin inomsebenzi we-anticancer, ivimbela umsebenzi we-PI3-kinase futhi ivimbela kancane umsebenzi we-PIP Kinase, inciphisa ukukhula kwamangqamuzana omdlavuza ngokusebenzisa uhlobo lwe-II lwe-estrogen receptors.

3.I-Quercetin ingase ivimbele ukukhululwa kwe-histamine kuma-basophil nama-mast cells.

4. I-Quercetin ingase ilawule ukusakazeka kwamagciwane athile emzimbeni.

I-5, i-Quercetin ingasiza ekunciphiseni ukubhujiswa kwezicubu.

6.I-Quercetin ingase futhi ibe usizo ekwelapheni i-dysentery, gout, ne-psoriasis

Ukufaka Isici Impendulo Yokulimala Kwe-DNA Ngama-Algorithms Okulandelela Iseli kanye Nokuhlelwa Kwezici Zeseli Kusetshenziswa Ukuhlaziya Okuphezulu Kokudlula Kwesikhathi Kokuqukethwe. U-Walter Georgescu et al (2015), PLoS ONE https://dx.doi.org/10.1371/journal.pone.0129438

Ngokwesiko, i-kinetics yokulungiswa kwe-DNA ilinganiselwa kusetshenziswa i-immunocytochemistry ngokulebula amaprotheni abandakanyeka ekuphenduleni komonakalo we-DNA (DDR) anezimpawu ze-fluorescent ekuhlolweni kweseli okungaguquki. Nokho, ulwazi oluningiliziwe lokuguquguquka kwe-DDR kuzo zonke izizukulwane zamaseli amaningi alikwazi ukutholwa kusetshenziswa inombolo elinganiselwe yamaphoyinti esikhathi eseli angashintshi. Lapha sibika ngokuguquguquka kwe-53BP1 ebangelwa imisebe ye-foci (RIF) kuzo zonke izizukulwane zamangqamuzana amaningi kusetshenziswa izithombe zeseli bukhoma zamaseli we-mammary epithelial cell (MCF10A) angewona amabi aveza i-histone H2B-GFP kanye nephrotheni yokulungisa i-DNA engu-53BP1-mCherry. Sisebenzisa ukukhishwa okuzenzakalelayo kwezici zokucabanga ze-RIF nezindlela zokuhlela ezilandelanayo, sikwazile ukuveza imininingwane enemininingwane ye-RIF kinetics amahora angama-24 ngaphambi namahora angama-24 ngemuva kokuchayeka kumithamo ephansi nephezulu yemisebe ye-ionizing. Ukuhlaziywa kokuqukethwe okuphezulu ezingeni leseli elilodwa ngaphezu kwamakhulu amaseli kusivumela ukuba silinganise ngokunembile ukuncika kwethamo lokukhiqizwa kwamaprotheni angu-53BP1, i-RIF yasendaweni yenuzi kanye nokunyakaza kwe-RIF ngemva kokuchayeka ku-X ray. Sisebenzisa izindlela zokubhalisa ezinwebekayo ezisuselwe kuphethini yenuzi yamaseli ngamanye, singachaza ukunyakaza kwe-RIF ngayinye ngokuqondile ngaphakathi kwenucleus. Sibonisa ukuthi ukulungiswa kwe-DNA kwenzeka enanini elilinganiselwe lezizinda ezinkulu, lapho ama-RIF amaningi amancane enza khona, ahlangane futhi/noma axazulule ngokunyakaza okungahleliwe kulandela umthetho ovamile wokusabalalisa. Ukwakheka kwe-foci enkulu kuboniswa ukuthi kwenzeka ikakhulukazi ngokuhlanganiswa kwe-RIF encane kunokuba ngokukhula kokugxila komuntu ngamunye. Silinganisela osayizi besizinda sokulungisa abangu-7.5 kuya ku-11 µm2 ngenombolo enkulu engu-~15 yezizinda ngeseli ye-MCF10A ngayinye. Lo msebenzi uphinde ugqamise i-DDR eqondene ngqo nemithamo emikhulu kune-1 Gy njengokunyuka okusheshayo kwamaprotheni angu-53BP1 ku-nucleus kanye namazinga okusabalalisa kwe-foci ashesha kakhulu kunokunyakaza kwe-foci okuzenzakalelayo. Sicabanga ukuthi ukuhlanganisa kwe-RIF kubonisa inqubo “ecindezelwe” yokulungisa i-DNA ethathwe ngaphandle kwezimo zomzimba lapho i-DSB eminingi yenzeka ngesikhathi esisodwa. Imithamo ephezulu yemisebe ye-ionizing iholela ekuhlanganisweni kwe-RIF nezizinda zokulungisa okubuye kwandise ukusondela kwe-DSB nokulungisa kabi. Ngakho-ke ukuthola okunjalo kungase kubaluleke kakhulu ukuchaza ukuncika komthamo omkhulu wokuhlelwa kabusha kwechromosomal nokufa kweseli kukalwa ngemva kokuchayeka emisebeni ye-ionizing.

Izindonga zamaseli we-microalgae zenziwe nge-polysaccharide alginate engashiswa futhi icindezelwe ukuze yenze ipulasitiki enamandla amakhulu, ebuye ibole. Nazi ezinye izibonelo zemikhiqizo eyenziwe ngale nto.