[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

UCI Chem 51C: Organic Chemistry (Spring 2015)
Lec 24. Organic Chemistry — Fischer Projections
View the complete course: https://ocw.uci.edu/courses/chem_51c_organic_chemistry.html
Instructor: Susan King, Ph.D.

License: Creative Commons CC-BY-SA
Terms of Use: https://ocw.uci.edu/info
More courses at https://ocw.uci.edu

Description: This is the third (and final) quarter of the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds.

Organic Chemistry (Chem 51C) is part of OpenChem: https://ocw.uci.edu/collections/open_chemistry.html
This video is part of a 27-lecture undergraduate-level course titled “Organic Chemistry” taught at UC Irvine by Professor Susan King.

Recorded May 29, 2015

Index of Topics:
00:41 – Monosaccharides
01:08 – Fischer Projection
12:16 – Disaccharide
13:04 – Oligosaccharide
13:35 – Polysaccharide
14:01 – Monosaccharide can be Classified by Three Criteria
15:33 – The D Family of Sugars
17:39 – The L Family of Sugars
23:09 – Epimers
25:01 – Cyclic Structures of Monosaccharides
44:08 – Haworth Projection
45:15 – Chair Conformation

Required attribution: King, Susan.Chem 51C (UCI OpenCourseWare: University of California, Irvine), https://ocw.uci.edu/courses/chem_51c_organic_chemistry.html. [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License. (https://creativecommons.org/licenses/by-sa/3.0/deed.en_US).

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