[Latin Name] Rhodiola Rosea

[Plant Source] China

[Specifications] Salidrosides:1%-5%

Rosavin:3% HPLC

[Appearance] Brown fine powder

[Plant Part Used] Root

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Package] Packed in paper-drums and two plastic-bags inside.

[What is Rhodiola Rosea]

Rhodiola Rosea (also known as Arctic root or golden root) is a member of the family Crassulaceae, a family of plants native to the arctic regions of Eastern Siberia. Rhodiola rosea is widely distributed  in Arctic and mountainous regions throughout Europe and Asia. It grows at altitudes of 11,000 to 18,000 feet above sea level.

There are numerous animal and test tube studies showing that rhodiola has both a stimulating and a sedating effect on the central nervous system; enhance physical endurance; improves thyroid, thymus, and adrenal function; protects the nervous system, heart and liver; and has antioxidant and anticancer properties.

[Function]

1 Enhancing immunity and delaying aging;

2 Resisting radiation and tumor;

3 Regulating nervous system and metabolism, effectively limiting melancholy feeling and mood, and promoting mental status;

4 Protecting cardiovascular, dilating coronary artery,preventing coronary arteriosclerosis and arrhythmia.

UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Lec 14. Introduction to Chemical Biology — Glycobiology
View the complete course: https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html
Instructor: Gregory Weiss, Ph.D.

License: Creative Commons BY-NC-SA
Terms of Use: https://ocw.uci.edu/info.
More courses at https://ocw.uci.edu

Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.

Introduction to Chemical Biology (Chem 128) is part of OpenChem: https://ocw.uci.edu/collections/open_chemistry.html
This video is part of a 18-lecture undergraduate-level course titled “Introduction to Chemical Biology” taught at UC Irvine by Professor Gregory Weiss.

Recorded February 22. 2013.

Index of Topics:
0:02:04 Enzyme Functions
0:06:10 Serine Based Proteases
0:10:44 Protein Based Inhibition of Proteases
0:13:10 Covalent or Mechanism-Based Protease Inhibitors
0:15:02 Inhibition of Serine Esterases
0:17:07 Enzymes Use Co-Factors (Vitamins)
0:21:31 The Origins of Stereospecificity in Alcohol Dehydrogenase
0:24:09 Pyridozal Phosphate (Vitamin 86)
0:27:29 PLP – Catalyzed Transamination
0:29:29 Protein Engineering
0:36:16 Most Mutations Make the Protein Less Functional
0:38:17 Carbohydrates
0:44:30 Hemiacetal Reactivity and Formation
0:46:33 Glucopyranose is the Most Noteable Ring Configuration
0:47:51 Oligosaccharides of the TB Coat
0:51:29 Oxocarbenium Ions as a Key Intermediate in Hydrolysis of Glycosidic Bonds
0:53:19 Mechanisms of Enzymatic Hydrolysis
0:54:58 Commonalitites in Glycosylhydrolase Mechanisms
0:56:03 Neuraminidase: Key Enzyme in Influenza Release from Surface to Cell
1:01:06 Oligosaccharides
1:04:22 Polysaccharides
1:08:04 Hyaluronan: Oligosaccharides in Joints
1:09:57 Glycosylated Proteins

Required attribution: Weiss, Gregory Introduction to Chemical Biology 128 (UCI OpenCourseWare: University of California, Irvine), https://ocw.uci.edu/courses/chem_128_introduction_to_chemical_biology.html. [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License (https://creativecommons.org/licenses/by-sa/3.0/us/deed.en_US).

Pneumococcal polysaccharide vaccine—the latest version is known as Pneumovax 23—is the first pneumococcal vaccine, the first vaccine derived from a capsular polysaccharide, and an important landmark in medical history. The polysaccharide antigens were used to induce type-specific antibodies that enhanced opsonization, phagocytosis, and killing of Streptococcus pneumoniae bacteria by phagocytic immune cells. The pneumococcal polysaccharide vaccine is widely used in high-risk adults. As a result, there have been important reductions in the incidence, morbidity, and mortality from invasive pneumococcal disease.
First used in 1945, the tetravalent vaccine was not widely distributed, since its deployment coincided with the discovery of penicillin. In the 1970s, Robert Austrian championed the manufacture and distribution of a 14-valent PPSV. This evolved in 1983 to a 23-valent formulation. A significant breakthrough affecting the burden of pneumococcal disease was the licensing of a protein conjugate heptavalent vaccine beginning in February 2000.

This video is targeted to blind users.

Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video