[Latin Name] Griffonia simplicifolia

[Plant Source] Griffonia Seed

[Specifications] 98%; 99% HPLC

[Appearance] White fine powder

Plant Part Used: Seed

[Particle size] 80 Mesh

[Loss on drying] ≤5.0%

[Heavy Metal] ≤10PPM

[Pesticide residue] EC396-2005, USP 34, EP 8.0, FDA

[Storage] Store in cool & dry area, keep away from the direct light and heat.

[Shelf life] 24 Months

[Package] Packed in paper-drums and two plastic-bags inside.

[Net weight] 25kgs/drum

[What is 5-HTP]

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson’s disease.

 [How does it work?]

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

[Function]

Depression. Some clinical research shows that taking 5-HTP by mouth improve symptoms of depression in some people. Some clinical research shows that taking 5-HTP by mouth might be as beneficial as certain prescription antidepressant drugs for improving depression symptoms. In most studies, 150-800 mg daily of 5-HTP was taken. In some cases, higher doses have been used.

Down syndrome. Some research shows that giving 5-HTP to infants with Down syndrome might improve muscle and activity. Other research shows that it does not improve muscle or development when taken from infancy until 3-4 years of age. Research also shows that taking 5-HTP along with conventional prescription drugs does improve development, social skills, or language skills.

Anxiety 5-HTP was found to be protective against carbon dioxide-induced panic attacks. One study compared 5-HTP and the prescription medication clomipramine for anxiety. Clomipramine is a tricyclic antidepressant used for treating obsessive-compulsive disorder. 5-HTP was found to be somewhat effective in reducing anxiety symptoms, but not as effective as clomipramine.

Sleep 5-HTP supplements fared a little better for insomnia.5-HTP decreased the time required to get to sleep and decreased the number of nighttime awakenings. Taking 5-HTP along with GABA (gamma-aminobutyric acid), a relaxing neurotransmitter, reduced the time it took to fall asleep and increased the duration and quality of sleep. One study found that children with night terrors benefited from 5-HTP.

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Apple polyphenols are powerful antioxidants. They act as powerful anti-glycation agents and promote a healthy inflammatory response. Apple polyphenols also help support a healthy cardiovascular system, cell division, blood sugar levels already within normal range, and healthy immune function.

Benefits at a Glance:

Lowers oxidative stress
Supports blood sugar levels already within the normal range
Supports cardiovascular health
Supports healthy cell division in the colon
Apple Polyphenols May Extend Life by Lowering Oxidative Stress

Apple skins contain many of the polyphenols found in other fruits, but in higher concentrations. One of those compounds is a polyphenol called phloridzin.1-3 Scientists conducting initial investigations found that the use of apple polyphenols increased the life span of various species by 10% to 12% by ramping up gene expression of vital natural cellular antioxidant systems.4-6

Phloridzin Supports Healthy Blood Sugar Levels Already Within Normal Range

The apple polyphenol phloridzin is especially active against glycation, one of the most common causes of normal aging. Phloridzin attacks glycation and its effects at many different levels, starting with blood sugar. Studies show that phloridzin significantly inhibits glucose uptake into intestinal cells, as well as the active transport of glucose out of those cells and into the bloodstream.2-7

Some sugar, of course, is inevitably absorbed, where it forms carbonyl molecules which react with proteins and DNA to form advanced glycation end-products, or AGEs. Phloridzin prevents formation of those carbonyl compounds. Phloridzin also traps any remaining carbonyls that are produced, inhibiting them from reacting with more vulnerable body molecules.3,8,9

Supports Cardiovascular Health

Animal studies show that apple polyphenols slow triglyceride absorption by blocking pancreatic lipase, an enzyme specifically required to break down triglyceride fats.10,11 Blocking pancreatic lipase causes some triglycerides to pass out of the body as waste.12 Additional research has shown that apple polyphenols can increase the protective antioxidant molecule, paraoxonase, by as much as 23%13 to inhibit lipid peroxidation and inflammatory factors.

Supports Healthy Cell Division in the Colon

Apple polyphenols promote colon health by scavenging oxygen free radicals, a potent means of increasing cellular mechanisms and supporting DNA function.14,15 They also enhance production of natural antioxidant enzymes that colon cells use to protect themselves,16-19 inhibit enzymes which produce inflammatory cytokines,20-23 and have been shown to help protect the DNA of colon cells.18,24 Since health conscious people today obtain a wide range of polyphenols (such as green tea and pomegranate extracts), a daily dose of 300 mg to 600 mg of apple polyphenols may be all that is needed to obtain desired benefits.

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DISCLAIMER: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed and results may vary.
The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician. SEE FULL WARNINGS ON LIFE EXTENSION WEBSITE.