Mhodzi yembeu yemazambiringa, iyo inogadzirwa kubva kumbeu yewaini yewaini, inosimudzirwa sechikafu chekuwedzera kwemamiriro akasiyana-siyana, kusanganisira kusakwana kwevenous (apo tsinga dzine dambudziko rekutumira ropa kubva kumakumbo kudzokera kumoyo), kukurudzira kupora kweronda, uye kuderedza kuzvimba.

Mbeu yemazambiringa inotorwa ine proanthocyanidins, iyo yakadzidziswa kune akasiyana ehutano mamiriro.

Kubva kuGreece yekare, zvikamu zvakasiyana-siyana zvemazambiringa zvakashandiswa pakurapa. Kune mishumo yevaIjipita vekare uye vekuEurope vakashandisa mazambiringa nembeu yemazambiringa zvakare.

Nhasi, tinoziva kuti mbeu yemazambiringa inotorwa ine oligomeric proanthocyanidin (OPC) an antioxidant iyo inotendwa kuvandudza mamwe mamiriro ehutano. Humwe humbowo hwesainzi hunotsigira kushandiswa kwembeu yemazambiringa kana mhodzi yemuzambiringa kuderedza kuyerera kweropa mumakumbo uye kuderedza kushushikana kwemaziso nekuda kwekupenya.